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Rac GTPase Activating Protein 1 产品

(Rac GTPase Activating Protein 1 (RACGAP1))

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The protein encoded by this gene belongs to the GTPase-activating protein (GAP) family. GAPs bind activated forms of Rho GTPases and stimulate GTP hydrolysis. Through this catalytic function, GAPs negatively regulate Rho-mediated signals. This protein plays a regulatory role in initiation of cytokinesis, controlling cell growth and differentiation of hematopoietic cells, regulating spermatogenesis, and in neuronal proliferation. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2011].

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Featured Rac GTPase Activating Protein 1 Categories

Rac GTPase Activating Protein 1 抗体

High quality antibodies with extensive validation data.

Rac GTPase Activating Protein 1 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

Rac GTPase Activating Protein 1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Rac GTPase Activating Protein 1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (4)
  • (5)
Cat. No. ABIN565414
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF, FACS
Validations
  • (7)
Cat. No. ABIN184690
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF, IHC (p), ICC
Validations
  • (1)
  • (5)
Cat. No. ABIN2856889
Quantity 100 μL
Datasheet Datasheet

Recommended Rac GTPase Activating Protein 1 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6962157
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6959035
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6959034
Quantity 96 tests
Datasheet Datasheet

Recommended Rac GTPase Activating Protein 1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1317259
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
Cat. No. ABIN3095022
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
Cat. No. ABIN3137551
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our Rac GTPase Activating Protein 1 Products

Renshaw, Panagiotou, Lavoie, Wilde: "CDK11p58-cyclin L1β regulates abscission site assembly." in: The Journal of biological chemistry, Vol. 294, Issue 49, pp. 18639-18649, (2019) (PubMed).

Yang, Cao, He, Li, Feng, Zhang, Zhang, Wang, Yang, Zhu, Nie, Jiang, Tian, Zhang, Liu, Ji, Zhu, Xia, Zhang: "Overexpression of Rac GTPase Activating Protein 1 Contributes to Proliferation of Cancer Cells by Reducing Hippo Signaling to Promote Cytokinesis." in: Gastroenterology, Vol. 155, Issue 4, pp. 1233-1249.e22, (2018) (PubMed).

Jungas, Perchey, Fawal, Callot, Froment, Burlet-Schiltz, Besson, Davy: "Eph-mediated tyrosine phosphorylation of citron kinase controls abscission." in: The Journal of cell biology, Vol. 214, Issue 5, pp. 555-69, (2017) (PubMed).

Lekomtsev, Su, Pye, Blight, Sundaramoorthy, Takaki, Collinson, Cherepanov, Divecha, Petronczki: "Centralspindlin links the mitotic spindle to the plasma membrane during cytokinesis." in: Nature, Vol. 492, Issue 7428, pp. 276-9, (2012) (PubMed).

Wang, Ooi, Hui: "Upregulation of Rac GTPase-activating protein 1 is significantly associated with the early recurrence of human hepatocellular carcinoma." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 17, Issue 18, pp. 6040-51, (2011) (PubMed).

Wolfe, Takaki, Petronczki, Glotzer: "Polo-like kinase 1 directs assembly of the HsCyk-4 RhoGAP/Ect2 RhoGEF complex to initiate cleavage furrow formation." in: PLoS biology, Vol. 7, Issue 5, pp. e1000110, (2009) (PubMed).

Burkard, Maciejowski, Rodriguez-Bravo, Repka, Lowery, Clauser, Zhang, Shokat, Carr, Yaffe, Jallepalli: "Plk1 self-organization and priming phosphorylation of HsCYK-4 at the spindle midzone regulate the onset of division in human cells." in: PLoS biology, Vol. 7, Issue 5, pp. e1000111, (2009) (PubMed).

Nishimura, Yonemura: "Centralspindlin regulates ECT2 and RhoA accumulation at the equatorial cortex during cytokinesis." in: Journal of cell science, Vol. 119, Issue Pt 1, pp. 104-14, (2005) (PubMed).

Reibel, Dorseuil, Stancou, Bertoglio, Gacon: "A hemopoietic specific gene encoding a small GTP binding protein is overexpressed during T cell activation." in: Biochemical and biophysical research communications, Vol. 175, Issue 2, pp. 451-8, (1991) (PubMed).

Synonyms and alternative names related to Rac GTPase Activating Protein 1

Rac GTPase activating protein 1 (RACGAP1), Rac GTPase activating protein 1 (racgap1), rac GTPase-activating protein 1 (RACGAP1), Rac GTPase activating protein 1 L homeolog (racgap1.L), Rac GTPase activating protein 1 L homeolog (racgap1.2.L), Rac GTPase activating protein 1 (racgap1.2), RAS p21 protein activator 1 (Rasa1), Rac GTPase-activating protein 1 (Racgap1), Rac GTPase activating protein 1 (Racgap1), si:ch1073-416j23.1 (si:ch1073-416j23.1), AI227039, AI327394, Band25, cyk-4, CYK4, Gap, GAPX, gtl11, GTPase, HsCYK-4, ID-GAP, id-gap, MGC121578, MgcRacGAP, mgcracgap, mKIAA1478, RACGAP1, Rasa, RasGAP, wu:fb92c08, zgc:77839

Protein level used designations for Rac GTPase Activating Protein 1

  • GTPase activating protein
  • male germ cell RacGap
  • protein CYK4 homolg
  • protein CYK4 homolog
  • rac GTPase-activating protein 1
  • Rac GTPase-activating protein 1
  • Rac GTPase activating protein 1
  • rac GTPase-activating protein 1-like
  • GTPase-activating protein
  • p120-rasGAP
  • GAP
  • RAS p21 protein activator 1
  • p120GAP
  • ras GTPase-activating protein 1
  • rasGAP
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