Protein tyrosine Phosphatase, Receptor Type, J 产品
(Protein tyrosine Phosphatase, Receptor Type, J (PTPRJ))
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The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes, including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region containing five fibronectin type III repeats, a single transmembrane region, and a single intracytoplasmic catalytic domain, and thus represents a receptor-type PTP. This protein is present in all hematopoietic lineages, and was shown to negatively regulate T cell receptor signaling possibly through interfering with the phosphorylation of Phospholipase C Gamma 1 and Linker for Activation of T Cells. This protein can also dephosphorylate the PDGF beta receptor, and may be involved in UV-induced signal transduction. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Protein tyrosine Phosphatase, Receptor Type, J 抗体
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Protein tyrosine Phosphatase, Receptor Type, J ELISA试剂盒
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Protein tyrosine Phosphatase, Receptor Type, J 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Protein tyrosine Phosphatase, Receptor Type, J 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (8)
Cat. No.
ABIN7441778
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, ICC, IHC (p), IHC (fro)
Validations
- (4)
Cat. No.
ABIN7440614
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, FACS, ICC, Neut
Validations
- (4)
Cat. No.
ABIN7193256
Quantity
0.1 mg
Datasheet
Datasheet
Recommended Protein tyrosine Phosphatase, Receptor Type, J ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6969755
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6958961
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN4882596
Quantity
96 tests
Datasheet
Datasheet
Recommended Protein tyrosine Phosphatase, Receptor Type, J 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7124686
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1316873
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
- (1)
Cat. No.
ABIN3094860
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our Protein tyrosine Phosphatase, Receptor Type, J Products
: "A novel splice variant of the protein tyrosine phosphatase PTPRJ that encodes for a soluble protein involved in angiogenesis." in: Oncotarget, Vol. 8, Issue 6, pp. 10091-10102, (2018) (PubMed).: "The protein tyrosine phosphatase DEP-1/PTPRJ promotes breast cancer cell invasion and metastasis." in: Oncogene, Vol. 34, Issue 44, pp. 5536-47, (2015) (PubMed).
: "Phosphorylation of DEP-1/PTPRJ on threonine 1318 regulates Src activation and endothelial cell permeability induced by vascular endothelial growth factor." in: Cellular signalling, Vol. 26, Issue 6, pp. 1283-93, (2014) (PubMed).
: "Polymorphisms of protein tyrosine phosphatase CD148 influence FcγRIIA-dependent platelet activation and the risk of heparin-induced thrombocytopenia." in: Blood, Vol. 120, Issue 6, pp. 1309-16, (2012) (PubMed).
: "Systematic validation of specific phenotypic markers for in vitro polarized human macrophages." in: Journal of immunological methods, Vol. 375, Issue 1-2, pp. 196-206, (2012) (PubMed).
: "Regulation of Src family kinases involved in T cell receptor signaling by protein-tyrosine phosphatase CD148." in: The Journal of biological chemistry, Vol. 286, Issue 25, pp. 22101-12, (2011) (PubMed).
: "Expression profiles of novel cell surface molecules on B-cell subsets and plasma cells as analyzed by flow cytometry." in: Immunology letters, Vol. 134, Issue 2, pp. 113-21, (2010) (PubMed).
: "Analysis of HLDA9 mAbs on plasmacytoid dendritic cells." in: Immunology letters, Vol. 134, Issue 2, pp. 167-73, (2010) (PubMed).
: "Tumor suppressor density-enhanced phosphatase-1 (DEP-1) inhibits the RAS pathway by direct dephosphorylation of ERK1/2 kinases." in: The Journal of biological chemistry, Vol. 284, Issue 33, pp. 22048-58, (2009) (PubMed).
: "CD148 and CD27 are expressed in B cell lymphomas derived from both memory and naïve B cells." in: Leukemia & lymphoma, Vol. 43, Issue 9, pp. 1855-8, (2003) (PubMed).
Synonyms and alternative names related to Protein tyrosine Phosphatase, Receptor Type, J
acid phosphatase 1 (ACP1), protein tyrosine phosphatase, receptor type J (PTPRJ), protein tyrosine phosphatase, receptor type, J (Ptprj), protein tyrosine phosphatase, receptor type, J (PTPRJ), protein tyrosine phosphatase, receptor type, J (EUBREC_2762), AI450271, BET, Byp, CD148, DEP-1, DEP1, HAAP, HPTPeta, Ptpb2, PTPbeta2, PTPRJ, R-PTP-ETA, RPTPJ, Scc-1, SCC1, Scc1Protein level used designations for Protein tyrosine Phosphatase, Receptor Type, J
- LMW-PTP
- LMW-PTPase
- acid phosphatase of erythrocyte
- adipocyte acid phosphatase
- cytoplasmic phosphotyrosyl protein phosphatase
- low molecular weight cytosolic acid phosphatase
- low molecular weight phosphotyrosine protein phosphatase
- protein tyrosine phosphatase
- red cell acid phosphatase 1
- CD148 antigen
- DEP-1
- HPTP eta
- R-PTP-J
- density-enhanced phosphatase 1
- human density enhanced phosphatase-1
- protein tyrosine phosphatase, receptor type, J polypeptide
- protein-tyrosine phosphatase eta
- protein-tyrosine phosphatase receptor type J
- receptor-type tyrosine-protein phosphatase eta
- susceptibility to colon cancer 1, mouse, homolog of
- HPTP beta-like tyrosine phosphatase
- R-PTP-eta
- colon tumor susceptibility 1
- susceptibility to colon cancer 1
- density enhanced phosphatase-1
- supporting-cell antigen
- protein tyrosine phosphatase, receptor type, J
- receptor-type tyrosine-protein phosphatase eta-like
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