TGFA 蛋白
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- 抗原 See all TGFA 蛋白
- TGFA (Transforming Growth Factor, alpha (TGFA))
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 序列
- VVSHFNDCPD SHTQFCFHGT CRFLVQEDKP ACVCHSGYVG ARCEHADLLA
- 产品特性
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Purified recombinant Human TGF alpha protein
Expression System: E.coli
Bioactivity: The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BALB/c 3T3 cells is ? 0.2 ng/mL, corresponding to a specific activity of ? 5 x 10^6 units/mg. - 纯度
- > 98 % pure
- 内毒素水平
- < 0.1 ng per μg (1 EU/μg).
- Top Product
- Discover our top product TGFA 蛋白
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 说明
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Biological activity: The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BALB/c 3T3 cells is approx. 0.2 ng/mL, corresponding to a specific activity of approx. 5 x 10^6 units/mg.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Reconstitute in water to a concentration of 0.1 - 1.0 mg/mL.
- 缓冲液
- Supplied lyophilized with no additives.
- 储存液
- Without preservative
- 注意事项
- Avoid repeated freeze/thaw cycles.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
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- 抗原
- TGFA (Transforming Growth Factor, alpha (TGFA))
- 别名
- TGF alpha (TGFA 产品)
- 别名
- TFGA Protein, LOC100009482 Protein, TGF alpha Protein, TGFA Protein, wa-1 Protein, wa1 Protein, RATTGFAA Protein, TGFAA Protein, NV15606 Protein, si:ch211-10e8.7 Protein, transforming growth factor alpha Protein, transforming growth factor alpha L homeolog Protein, transforming growth factor-alpha Protein, transforming growth factor, alpha Protein, TGFA Protein, TGF-A Protein, Tgfa Protein, tgfa.L Protein, LOC100121300 Protein, LOC100009150 Protein, tgfa Protein
- 背景
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TGF alpha is an EGF-related polypeptide growth factor that signals through the EGF receptor, and stimulates the proliferation of a wide range of epidermal and epithelial cells. It is produced by monocytes, keratinocytes, and various tumor cells. TGF alpha induces transformation anchorage independence in cultured cells. Human, Mouse and rat TGF alpha are cross-species reactive. Recombinant human TGF alpha is a 50 amino acid polypeptide (5.5 kDa) which shares approximately 40 % sequence homology with EGF, including 6 conserved cysteine residues, which form 3 intramolecular disulfide bonds.
Alternative Names: TGF-alpha protein, TGFa protein, Transforming Growth Factor alpha protein, TGF a protein, TGFalpha protein - 分子量
- 5.5 kDa
- 途径
- NF-kappaB Signaling, RTK signaling, EGFR Signaling Pathway
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