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TGFA 蛋白

TGFA 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 98 % pure Active
产品编号 ABIN935809
发货至: 中国
  • 抗原 See all TGFA 蛋白
    TGFA (Transforming Growth Factor, alpha (TGFA))
    蛋白类型
    Recombinant
    生物活性
    Active
    宿主
    • 15
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    • 3
    • 3
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    资源
    • 21
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    大肠杆菌(E. Coli)
    序列
    VVSHFNDCPD SHTQFCFHGT CRFLVQEDKP ACVCHSGYVG ARCEHADLLA
    产品特性
    Purified recombinant Human TGF alpha protein
    Expression System: E.coli
    Bioactivity: The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BALB/c 3T3 cells is ? 0.2 ng/mL, corresponding to a specific activity of ? 5 x 10^6 units/mg.
    纯度
    > 98 % pure
    内毒素水平
    < 0.1 ng per μg (1 EU/μg).
    Top Product
    Discover our top product TGFA 蛋白
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    说明

    Biological activity: The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BALB/c 3T3 cells is approx. 0.2 ng/mL, corresponding to a specific activity of approx. 5 x 10^6 units/mg.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstitute in water to a concentration of 0.1 - 1.0 mg/mL.
    缓冲液
    Supplied lyophilized with no additives.
    储存液
    Without preservative
    注意事项
    Avoid repeated freeze/thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
  • 抗原
    TGFA (Transforming Growth Factor, alpha (TGFA))
    别名
    TGF alpha (TGFA 产品)
    别名
    TFGA Protein, LOC100009482 Protein, TGF alpha Protein, TGFA Protein, wa-1 Protein, wa1 Protein, RATTGFAA Protein, TGFAA Protein, NV15606 Protein, si:ch211-10e8.7 Protein, transforming growth factor alpha Protein, transforming growth factor alpha L homeolog Protein, transforming growth factor-alpha Protein, transforming growth factor, alpha Protein, TGFA Protein, TGF-A Protein, Tgfa Protein, tgfa.L Protein, LOC100121300 Protein, LOC100009150 Protein, tgfa Protein
    背景
    TGF alpha is an EGF-related polypeptide growth factor that signals through the EGF receptor, and stimulates the proliferation of a wide range of epidermal and epithelial cells. It is produced by monocytes, keratinocytes, and various tumor cells. TGF alpha induces transformation anchorage independence in cultured cells. Human, Mouse and rat TGF alpha are cross-species reactive. Recombinant human TGF alpha is a 50 amino acid polypeptide (5.5 kDa) which shares approximately 40 % sequence homology with EGF, including 6 conserved cysteine residues, which form 3 intramolecular disulfide bonds.
    Alternative Names: TGF-alpha protein, TGFa protein, Transforming Growth Factor alpha protein, TGF a protein, TGFalpha protein
    分子量
    5.5 kDa
    途径
    NF-kappaB Signaling, RTK signaling, EGFR Signaling Pathway
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