IL-17A/F Protein (AA 26-158) (His-Avi Tag,Biotin)
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- 抗原 See all IL-17A/F 蛋白
- IL-17A/F (Interleukin-17 A/F Heterodimer (IL-17A/F))
- 蛋白类型
- Recombinant
- 产品特性
- AA 26-158
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宿主
- 小鼠
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资源
- HEK-293 Cells
- 标记
- This IL-17A/F protein is labelled with His-Avi Tag,Biotin.
- 原理
- Biotinylated Mouse IL-17A & F Protein
- 序列
- Ala26-Ala158 (IL-17A) & Arg29-Ala161 (IL-17F)
- 特异性
- Uni-Prot: Q62386 (IL-17A), Q7TNI7-1 (IL-17F)
- 产品特性
- Recombinant Biotinylated Mouse IL-17A & F Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Ala26-Ala158(IL-17A) & Arg29-Ala161(IL-17F).
- 纯度
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- 过滤
- 0.22 μm filtered
- 内毒素水平
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Mouse IL-17R alpha, hFc Tag at 2μg/ml (100μl/well) on the plate. Dose response curve for Biotinylated Mouse IL-17A&F, His Tag with the EC50 of 17.7ng/ml determined by ELISA. See testing image for detail.
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- Discover our top product IL-17A/F 蛋白
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Interleukin-17 A/F Heterodimer (IL-17A/F) (AA 26-158) protein (His-Avi Tag)
IL-17A/F 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin-17 A/F Heterodimer (IL-17A/F) (AA 24-155) protein (His tag)IL-17A/F 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin-17 A/F Heterodimer (IL-17A/F) protein (His-Avi Tag,Biotin)IL-17A/F 宿主: 人 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Interleukin-17 A/F Heterodimer (IL-17A/F) proteinIL-17A/F 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant
Interleukin-17 A/F Heterodimer (IL-17A/F) proteinIL-17A/F 宿主: 大鼠 宿主: 大肠杆菌（E. Coli） Recombinant
Interleukin-17 A/F Heterodimer (IL-17A/F) (AA 24-155) protein (His tag,AVI tag,Biotin)IL-17A/F 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
Interleukin-17 A/F Heterodimer (IL-17A/F) proteinIL-17A/F 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- 缓冲液
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- IL-17A/F (Interleukin-17 A/F Heterodimer (IL-17A/F))
- 别名
- IL-17A&F (IL-17A/F 产品)
- 别名
- il17-5 Protein, si:ch211-63o20.2 Protein, interleukin 17a/f3 Protein, il17a/f3 Protein
- 背景
- Interleukin-17A (IL-17A), also known as CTLA-8, is a 15-20 kDa glycosylated cytokine that plays an important role in anti-microbial and chronic inflammation. The six IL-17 cytokines (IL-17A-F) are encoded by separate genes but adopt a conserved cystine knot fold.IL-17A is a ligand for IL17RA and IL17RC. The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC. Involved in inducing stromal cells to produce proinflammatory and hematopoietic cytokines.
- 分子量
- 17.9 kDa(IL-17A)&14.9 kDa(IL-17F). Due to glycosylation, the protein migrates to 22-25 kDa&27-30 kDa based on Tris-Bis PAGE result.
- UniProt
- Q62386
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