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GDF15 Protein (AA 189-303) (Fc Tag,Biotin)

GDF15 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
产品编号 ABIN7274730
发货至: 中国
  • 抗原 See all GDF15 蛋白
    GDF15 (Growth Differentiation Factor 15 (GDF15))
    蛋白类型
    Recombinant
    产品特性
    AA 189-303
    宿主
    • 14
    • 4
    • 3
    • 2
    • 1
    小鼠
    资源
    • 13
    • 7
    • 3
    • 1
    HEK-293 Cells
    标记
    This GDF15 protein is labelled with Fc Tag,Biotin.
    原理
    Biotinylated Mouse GDF15 Protein (Primary Amine Labeling)
    序列
    Ser189-Ala303
    产品特性
    Recombinant Biotinylated Mouse GDF15 Protein (Primary Amine Labeling) is expressed from HEK293 with hFc tag at the N-Terminus.It contains Ser189-Ala303.
    纯度
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1EU per μg by the LAL method.
    Biological Activity Comment
    Immobilized Mouse GFRAL, His Tag at 2μg/ml (100μl/Well) on the plate. Dose response curve for Biotinylated Mouse GDF15, hFc Tag with the EC50 of 10ng/ml determined by ELISA. See testing image for detail.
    Top Product
    Discover our top product GDF15 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    缓冲液
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    GDF15 (Growth Differentiation Factor 15 (GDF15))
    别名
    GDF15 (GDF15 产品)
    别名
    GDF15 Protein, GDF-15 Protein, MIC-1 Protein, MIC1 Protein, NAG-1 Protein, PDF Protein, PLAB Protein, PTGFB Protein, SBF Protein, growth differentiation factor 15 Protein, GDF15 Protein, Gdf15 Protein
    背景
    Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and that GDF15 was necessary for surviving both bacterial and viral infections, as well as sepsis. The protective effects of GDF15 were largely independent of pathogen control or the magnitude of inflammatory response, suggesting a role in disease tolerance.
    分子量
    37.9 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result.
    UniProt
    Q9Z0J7
    途径
    SARS-CoV-2 Protein Interactome
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