NCR3 Protein (Fc Tag)
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- 抗原 See all NCR3 蛋白
- NCR3 (Natural Cytotoxicity Triggering Receptor 3 (NCR3))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This NCR3 protein is labelled with Fc Tag.
- 原理
- Human NKp30 / NCR3 / CD337 Protein, Llama IgG2b Fc Tag, low endotoxin
- 序列
- Leu 19 - Gly 135
- 产品特性
- Human NKp30, Llama IgG2b Fc Tag (NC3-H5256) is expressed from human 293 cells (HEK293). It contains AA Leu 19 - Gly 135 (Accession # NP_667341.1).
- 纯度
- >95 % as determined by SDS-PAGE.
- 内毒素水平
- Less than 0.01 EU per μg by the LAL method.
- Top Product
- Discover our top product NCR3 蛋白
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- 应用备注
- This protein carries a llama IgG2b Fc tag at the C-terminus. The protein has a calculated MW of 40.7 kDa. The protein migrates as 50-55 kDa under reducing (R) condition due to glycosylation.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH 7.5
- 储存条件
- -20 °C
- 储存方法
- -20°C
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- 抗原
- NCR3 (Natural Cytotoxicity Triggering Receptor 3 (NCR3))
- 别名
- NKp30 / NCR3 / CD337 (NCR3 产品)
- 别名
- MGC133750 Protein, 1C7 Protein, CD337 Protein, LY117 Protein, MALS Protein, NKp30 Protein, Nkp30 Protein, natural cytotoxicity triggering receptor 3 Protein, NCR3 Protein, Ncr3 Protein
- 背景
- Synonyms:NCR3,CD337,NKp30,1C7,LY117,MALS,Description:Natural cytotoxicity triggering receptor 3 (NCR3) is also known as Activating natural killer receptor p30, Natural killer cell p30-related protein (NK-p30), CD antigen CD337, 1C7, LY117. NCR3 /CD337 /NKp30 belongs to the natural cytotoxicity receptor (NCR) family. NCR3 /NKp30 contains one Ig-like (immunoglobulin-like) domain. NCR3 /NKp30 is selectively expressed by all resting and activated NK cells and weakly expressed in spleen. NCR3 is homodimer in the unliganted form. NCR3 interacts with CD3Z. NCR3 interacts with and is activated by binding to NCR3LG1 or BAG6. Engagement of NCR3 by BAG6 also promotes dendritic cell (DC) maturation, both through killing those DCs that did not properly acquire a mature phenotype, and inducing NK cells to release TNFA and IFNG, which promotes DC maturation.
- 分子量
- 40.7 kDa
- NCBI登录号
- NP_667341
- 途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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