PRKAA2 Protein (His tag)
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- 抗原 See all PRKAA2 蛋白
- PRKAA2 (Protein Kinase, AMP-Activated, alpha 2 Catalytic Subunit (PRKAA2))
- 蛋白类型
- Recombinant
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宿主
- 大鼠
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资源
- 大肠杆菌（E. Coli）
- 标记
- This PRKAA2 protein is labelled with His tag.
- 原理
- Recombinant Rat AMPK alpha2 Protein (His Tag)
- 序列
- Tyr16-Val195
- 产品特性
- A DNA sequence encoding the Rat AMPK alpha2 (Q09137-1) (Tyr16-Val195) was expressed with a polyhistidine tag at the N-terminus.
- 纯度
- >85 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product PRKAA2 蛋白
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Protein Kinase, AMP-Activated, alpha 2 Catalytic Subunit (PRKAA2) (AA 1-552) (Active) protein (GST tag)
PRKAA2 宿主: 人 宿主: Insect cells (Sf21) Recombinant SDS, Func Active
Protein Kinase, AMP-Activated, alpha 2 Catalytic Subunit (PRKAA2) (AA 340-552) protein (His-IF2DI Tag)PRKAA2 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses ELISA, WB
Protein Kinase, AMP-Activated, alpha 2 Catalytic Subunit (PRKAA2) (AA 453-552) protein (GST tag)PRKAA2 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Protein Kinase, AMP-Activated, alpha 2 Catalytic Subunit (PRKAA2) (AA 1-552) protein (GST tag)PRKAA2 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Protein Kinase, AMP-Activated, alpha 2 Catalytic Subunit (PRKAA2) (AA 1-552) protein (Strep Tag)Crystallography grade PRKAA2 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
Protein Kinase, AMP-Activated, alpha 2 Catalytic Subunit (PRKAA2) (AA 1-552) protein (Strep Tag)Crystallography grade PRKAA2 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
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- 限制
- 仅限研究用
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- 状态
- Frozen, Liquid
- 缓冲液
- Supplied as sterile 20 mM Tris,1 mM EDTA,25 % glycerol, pH 8.0
- 储存条件
- -20 °C
- 储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- 抗原
- PRKAA2 (Protein Kinase, AMP-Activated, alpha 2 Catalytic Subunit (PRKAA2))
- 别名
- AMPK alpha2 (PRKAA2 产品)
- 别名
- AMPK Protein, AMPK2 Protein, AMPKa2 Protein, PRKAA Protein, Ampk Protein, Ampka2 Protein, 2310008I11Rik Protein, A830082D05 Protein, AMPKalpha2 Protein, AMPKA2 Protein, ampk Protein, ampk2 Protein, prkaa Protein, prkaa1 Protein, PRKAA2 Protein, protein kinase AMP-activated catalytic subunit alpha 2 Protein, protein kinase, AMP-activated, alpha 2 catalytic subunit Protein, protein kinase, AMP-activated, alpha 2 catalytic subunit S homeolog Protein, PRKAA2 Protein, Prkaa2 Protein, prkaa2.S Protein, prkaa2 Protein
- 背景
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Background: The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia.
Synonym: 5'-AMP-activated protein kinase catalytic subunit alpha-2,AAPK2,ACACA kinase,Acetyl-CoA carboxylase kinase,AMPK alpha 2 chain,AMPK subunit alpha-2,AMPK2,AMPKa2,AMPKalpha2,HMGCR kinase,Hydroxymethylglutaryl-CoA reductase kinase,PRKAA,PRKAA2,Protein kinase AMP activated alpha 2 catalytic subunit,Protein kinase AMP activated catalytic subunit alpha 2
- 分子量
- 20 kDa
- 途径
- AMPK Signaling, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Carbohydrate Metabolic Process, Warburg Effect
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