PROCR Protein (His tag)
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- 抗原 See all PROCR 蛋白
- PROCR (Protein C Receptor, Endothelial (PROCR))
- 蛋白类型
- Recombinant
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宿主
- 大鼠
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资源
- HEK-293 Cells
- 标记
- This PROCR protein is labelled with His tag.
- 原理
- Recombinant Rat EPCR Protein (His Tag)
- 序列
- Met1-Ser213
- 产品特性
- A DNA sequence encoding the rat PROCR (Met1-Ser213) was expressed with a polyhistidine tag at the C-terminus.
- 纯度
- > 95 % as determined by SDS-PAGE
- 内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method
- Top Product
- Discover our top product PROCR 蛋白
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Protein C Receptor, Endothelial (PROCR) (AA 1-238) protein (GST tag)
PROCR 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Protein C Receptor, Endothelial (PROCR) protein (His tag)PROCR 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 96 % as determined by SDS-PAGE
Protein C Receptor, Endothelial (PROCR) protein (Fc Tag)PROCR 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 85 % as determined by SDS-PAGE
Protein C Receptor, Endothelial (PROCR) (AA 18-210) protein (His tag)Crystallography grade PROCR 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Protein C Receptor, Endothelial (PROCR) (AA 18-214) protein (His tag)Crystallography grade PROCR 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Protein C Receptor, Endothelial (PROCR) (AA 18-238) protein (rho-1D4 tag)Crystallography grade PROCR 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Protein C Receptor, Endothelial (PROCR) (AA 18-242) protein (rho-1D4 tag)Crystallography grade PROCR 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- PROCR (Protein C Receptor, Endothelial (PROCR))
- 别名
- EPCR (PROCR 产品)
- 别名
- PROCR Protein, CCCA Protein, CCD41 Protein, EPCR Protein, AI325044 Protein, Ccca Protein, Ccd41 Protein, Epcr Protein, protein C receptor Protein, protein C receptor, endothelial Protein, PROCR Protein, Procr Protein
- 背景
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Background: Endothelial protein C receptor (EPCR), also known as activated protein C receptor (APC receptor) or PROCR, is a receptor for Protein C. Protein C plays an important role in many metabolism processes in humans and other animals after activated by binding to Endothelial protein C receptor (EPCR). Because of the EPCR is found primarily on endothelial cells (cells on the inside of blood vessels), activated protein C is found maily near endothelial cells. Protein C is pleiotropic, with two main functions: anticoagulation and cytoprotection. Which function will be performed depend on whether or not protein C remains bind to EPCR after activated. The anticoagulation occurs when it does not. In this case, protein C functions as an anticoagulant by irreversibly proteolytically inactivating Factor Va and Factor VIIIa, turning them into Factor Vi and Factor VIIIi respectively. When still bound to EPCR, activated protein C performs its cytoprotective effects, acting on the effector substrate PAR-1, protease-activated receptor-1. To a degree, APC's anticoagulant properties are independent of its cytoprotective ones, in that expression of one pathway is not affected by the existence of the other.
Synonym: PROCR
- 分子量
- 23.2 kDa
- UniProt
- Q4V8I1
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