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IL2RG Protein (His tag)

IL2RG 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 99 % as determined by SDS-PAGE
产品编号 ABIN7321196
发货至: 中国
  • 抗原 See all IL2RG 蛋白
    IL2RG (Interleukin 2 Receptor, gamma (IL2RG))
    蛋白类型
    Recombinant
    宿主
    • 18
    • 10
    • 3
    • 1
    • 1
    大鼠
    资源
    • 13
    • 7
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    HEK-293 Cells
    标记
    This IL2RG protein is labelled with His tag.
    原理
    Recombinant Rat IL2RG/CD132 Protein (His Tag)
    序列
    Met1-Ala262
    产品特性
    A DNA sequence encoding the rat IL2RG (Q68FU6) (Met1-Ala262) was expressed, fused with a polyhistidine tag at the C-terminus.
    纯度
    > 99 % as determined by SDS-PAGE
    内毒素水平
    < 1.0 EU per μg of the protein as determined by the LAL method
    Top Product
    Discover our top product IL2RG 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile PBS, pH 7.4
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    IL2RG (Interleukin 2 Receptor, gamma (IL2RG))
    别名
    IL2RG/CD132 (IL2RG 产品)
    别名
    Ab2-183 Protein, Cd132 Protein, CD132 Protein, CIDX Protein, IL-2RG Protein, IMD4 Protein, P64 Protein, SCIDX Protein, SCIDX1 Protein, [g]c Protein, gamma(c) Protein, gc Protein, interleukin 2 receptor subunit gamma Protein, interleukin 2 receptor subunit gamma L homeolog Protein, interleukin 2 receptor, gamma chain Protein, IL2RG Protein, il2rg.L Protein, Il2rg Protein
    背景

    Background: The common gamma chain (γc) (or CD132), also known as interleukin-2 receptor subunit gamma or IL2RG, is a member of the type I cytokine receptor family expressed on most lymphocyte (white blood cell) populations, and its gene is found on the X-chromosome of mammals. The common gamma chain (γc) (or IL2RG), is a cytokine receptor sub-unit that is common to the receptor complexes for at least six different interleukin receptors: IL-2, IL-4, IL-7, IL-9, IL-15 and interleukin-21 receptor. It is a component of multiple cytokine receptors that are essential for lymphocyte development and function. X-linked severe combined immunodeficiency (XSCID) is a rare and potentially fatal disease caused by mutations of IL2RG, the gene encoding IL2RG. IL2RG was demonstrated to be a component of the IL-4 receptor on the basis of chemical cross-linking data, the ability of IL2RG to augment IL-4 binding affinity. The observation that IL-2R gamma is a functional component of the IL-4 receptor, together with the finding that IL-2R gamma associates with the IL-7 receptor, begins to elucidate why deficiency of this common gamma chain (gamma c) has a profound effect on lymphoid function and development, as seen in X-linked severe combined immunodeficiency.

    Synonym: IL2RG

    分子量
    29.5 kDa
    UniProt
    Q68FU6
    途径
    JAK/STAT Signaling, Growth Factor Binding
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