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MASP2 Protein (Fc Tag)

MASP2 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 90 % as determined by SDS-PAGE and Coomassie blue staining.
产品编号 ABIN7092694
发货至: 中国
  • 抗原 See all MASP2 蛋白
    MASP2 (Mannan-Binding Lectin serine Peptidase 2 (MASP2))
    蛋白类型
    Recombinant
    宿主
    • 6
    • 4
    • 3
    • 1
    资源
    • 6
    • 6
    • 1
    • 1
    HEK-293 Cells
    标记
    This MASP2 protein is labelled with Fc Tag.
    原理
    Recombinant human MASP2 protein with N-terminal Human Fc tag
    特异性
    HFc (Glu99-Ala330) MASP2 (Gln298-Ser684)
    产品特性
    Extracellular Domain Protein
    纯化方法
    affinity purification
    纯度
    The purity of the protein is greater than 90 % as determined by SDS-PAGE and Coomassie blue staining.
    Top Product
    Discover our top product MASP2 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstitute with deionized water
    缓冲液
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    有效期
    12 months
  • 抗原
    MASP2 (Mannan-Binding Lectin serine Peptidase 2 (MASP2))
    别名
    MASP2 (MASP2 产品)
    别名
    MAP19 Protein, MASP-2 Protein, MASP1P1 Protein, sMAP Protein, MAp19 Protein, mannan binding lectin serine peptidase 2 Protein, mannan-binding lectin serine peptidase 2 Protein, MASP2 Protein, Masp2 Protein
    背景
    Synonymes: MAP19, MASP-2, MASP1P1, sMAP
    Description: This gene encodes a member of the peptidase S1 family of serine proteases. The encoded preproprotein is proteolytically processed to generate A and B chains that heterodimerize to form the mature protease. This protease cleaves complement components C2 and C4 in order to generate C3 convertase in the lectin pathway of the complement system. The encoded protease also plays a role in the coagulation cascade through cleavage of prothrombin to form thrombin. Myocardial infarction and acute stroke patients exhibit reduced serum concentrations of the encoded protein. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
    分子量
    predicted molecular mass of 68.4 kDa after removal of the signal peptide.
    基因ID
    10747
    UniProt
    O00187
    途径
    Complement System
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