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SARS-CoV-2 Spike Protein (BA.2 - Omicron) (His tag)

宿主: SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Omicron 宿主: HEK-293 Cells Recombinant > 95% as determined by SDS-PAGE. > 90% as determined by SEC-MALS. ELISA, SDS
产品编号 ABIN7072153
发货至: 中国
  • 抗原 See all SARS-CoV-2 Spike 蛋白
    SARS-CoV-2 Spike
    蛋白类型
    Recombinant
    产品特性
    BA.2 - Omicron
    宿主
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    SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Omicron
    资源
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    HEK-293 Cells
    标记
    This SARS-CoV-2 Spike protein is labelled with His tag.
    应用范围
    ELISA, SDS-PAGE (SDS)
    原理
    SARS-CoV-2 Spike RBD, His Tag (BA.2/Omicron) (MALS verified)
    产品特性
    SARS-CoV-2 Spike RBD, His Tag (BA.2/Omicron) is expressed from human 293 cells (HEK293). It contains AA Arg 319 - Lys 537 (Accession # QHD43416.1 (G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H). The spike mutations are identified on the SARS-CoV-2 Omicron variant (Pango lineage: BA.2; GISAID clade: GRA; Nextstrain clade: 21L). This protein carries a polyhistidine tag at the C-terminus.
    纯度
    > 95% as determined by SDS-PAGE. > 90% as determined by SEC-MALS.
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product SARS-CoV-2 Spike 蛋白
  • 说明

    The protein has a calculated MW of 26.7 kDa. The protein migrates as 33-40 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

    限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.
    注意事项
    Please avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C/-80 °C
    储存方法
    For long term storage, the product should be stored at lyophilized state at -20°C or lower.This product is stable after storage at:
    4-8°C for 12 months in lyophilized state,
    -70°C for 3 months under sterile conditions after reconstitution.
    有效期
    12 monts
  • 抗原
    SARS-CoV-2 Spike
    Abstract
    SARS-CoV-2 Spike 产品
    别名
    E2 Protein, E2 glycoprotein precursor Protein, Surface Glycoprotein Protein, S Protein
    物质类
    Viral Protein
    背景
    It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
    分子量
    26.7 kDa
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