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CD73 Protein (AA 27-549) (mFc Tag)

NT5E 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
产品编号 ABIN7013523
发货至: 中国
  • 抗原 See all CD73 (NT5E) 蛋白
    CD73 (NT5E) (5'-Nucleotidase, Ecto (CD73) (NT5E))
    蛋白类型
    Recombinant
    生物活性
    Active
    产品特性
    AA 27-549
    宿主
    • 15
    • 8
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    资源
    • 16
    • 7
    • 5
    • 2
    • 1
    • 1
    • 1
    HEK-293 Cells
    标记
    This CD73 protein is labelled with mFc Tag.
    产品特性
    Human CD73 Protein, Mouse IgG2a Fc Tag (active enzyme)
    纯度
    >95 % as determined by SDS-PAGE.
    内毒素水平
    Less than 0.1 EU per μg by the LAL method.
    Top Product
    Discover our top product NT5E 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    51 mM Tris, 100 mM Glycine, 150 mM NaCl, pH 7.5
    储存条件
    -20 °C
  • 抗原
    CD73 (NT5E) (5'-Nucleotidase, Ecto (CD73) (NT5E))
    别名
    CD73 (NT5E 产品)
    别名
    CALJA Protein, CD73 Protein, E5NT Protein, NT Protein, NT5 Protein, NTE Protein, eN Protein, eNT Protein, zgc:63784 Protein, NT5E Protein, MGC114869 Protein, PSPTO2277 Protein, 2210401F01Rik Protein, AI447961 Protein, Nt5 Protein, 5'-nucleotidase ecto Protein, 5'-nucleotidase, ecto (CD73) Protein, 5'-nucleotidase Protein, 5' nucleotidase, ecto Protein, NT5E Protein, nt5e Protein, nt5e.S Protein, PSPTO_2277 Protein, CBU_1233 Protein, MCA1322 Protein, Nt5e Protein
    背景
    5'-nucleotidase (5'-NT), also known as ecto-5'-nucleotidase or CD73 (cluster of differentiation 73), is an enzyme that is encoded by the NT5E gene. CD73 commonly serves to convert AMP to adenosine. Ecto-5-prime-nucleotidase (5-prime-ribonucleotide phosphohydrolase) catalyzes the conversion at neutral pH of purine 5-prime mononucleotides to nucleosides, the preferred substrate being AMP. Other forms of 5-prime nucleotidase exist in the cytoplasm and lysosomes and can be distinguished from ecto-NT5 by their substrate affinities, requirement for divalent magnesium ion, activation by ATP, and inhibition by inorganic phosphate. Rare allelic variants are associated with a syndrome of adult-onset calcification of joints and arteries (CALJA) affecting the iliac, femoral, and tibial arteries reducing circulation in the legs and the joints of the hands and feet causing pain.
    分子量
    84.9 kDa
    NCBI登录号
    NP_002517
    途径
    Synaptic Membrane, Ribonucleoside Biosynthetic Process
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