CD20 Protein (AA 1-297) (His tag,AVI tag,Biotin)
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- 抗原 See all CD20 (MS4A1) 蛋白
- CD20 (MS4A1) (Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 1-297
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This CD20 protein is labelled with His tag,AVI tag,Biotin.
- 特异性
- Biotinylation of this product is performed using Avitag™ technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin.
- 产品特性
- Biotinylated Human CD20 / MS4A1 Full Length Protein, His,Avitag™ (Nanodisc) (HEK293)
- 纯度
- >90 % as determined by SDS-PAGE.
- 内毒素水平
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product MS4A1 蛋白
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Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1) (AA 141-188) protein (His-Avi Tag)
MS4A1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by Tris-Bis PAGE
Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1) (AA 141-188) protein (His-Avi Tag,Biotin)MS4A1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by Tris-Bis PAGE
Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1) (AA 1-297) (Active) protein-VLPMS4A1 宿主: 人 宿主: HEK-293 Cells VLP > 95 % as determined by HPLC Imm, ELISA, Func, SPR Active
Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1) (AA 1-297) (Active) protein-VLP (Biotin)MS4A1 宿主: 人 宿主: HEK-293 Cells VLP > 95 % as determined by HPLC Imm, ELISA, Func, SPR Active
Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1) (AA 1-297) protein (GST tag)MS4A1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1) (AA 1-297) (Active) protein (His tag)MS4A1 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1) (AA 1-297) (Active) protein (His tag)MS4A1 宿主: 人 宿主: HEK-293 Cells Recombinant >85 % as determined by SDS-PAGE. Active
Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1) (AA 141-188) protein (His-IF2DI Tag)MS4A1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1) (AA 210-297) protein (GST tag)MS4A1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1) protein (TRX tag)MS4A1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 80 % as determined by reducing SDS-PAGE.
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- 说明
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Ready-to-use Avitag™ biotinylated protein:
The product is exclusively produced using the Avitag™ technology. Briefly, a unique 15 amino acid peptide, the Avi tag, is introduced into the recombinant protein during expression vector construction. The single lysine residue in the Avi tag is enzymatically biotinylated by the E. Coli biotin ligase BirA.
This single-point enzymatic labeling technique brings many advantages for commonly used binding assays. The biotinylation happens on the lysine residue of Avi tag, and therefore does NOT interfere with the target protein's natural binding activities. In addition, when immobilized on an avidin-coated surface, the protein orientation is uniform because the position of the Avi tag in the protein is precisely controlled. - 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- 20 mM HEPES, 150 mM NaCl, pH 7.5
- 储存条件
- -20 °C
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- 抗原
- CD20 (MS4A1) (Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1))
- 别名
- CD20 (MS4A1 产品)
- 别名
- B1 Protein, Bp35 Protein, CD20 Protein, CVID5 Protein, LEU-16 Protein, MS4A2 Protein, S7 Protein, AA960661 Protein, Cd20 Protein, Ly-44 Protein, Ms4a2 Protein, MS4A1 Protein, bp35 Protein, cd20 Protein, ms4a2 Protein, leu-16 Protein, ms4a4c Protein, cd20-like Protein, membrane spanning 4-domains A1 Protein, membrane-spanning 4-domains, subfamily A, member 1 Protein, B-lymphocyte antigen CD20 Protein, MS4A1 Protein, Ms4a1 Protein, ms4a1 Protein, LOC101694281 Protein
- 背景
- B-lymphocyte antigen CD20 is also known as B-lymphocyte surface antigen B1, Leukocyte surface antigen Leu-16, Membrane-spanning 4-domains subfamily A member 1 and MS4A1, is an activated-glycosylated phosphoprotein expressed on the surface of all B-cells beginning at the pro-B phase (CD45R+, CD117+) and progressively increasing in concentration until maturity. CD20 is expressed on all stages of B cell development except the first and last, it is present from late pro-B cells through memory cells, but not on either early pro-B cells or plasma blasts and plasma cells. It is found on B-cell lymphomas, hairy cell leukemia, B-cell chronic lymphocytic leukemia, and melanoma cancer stem cells. The protein has no known natural ligand and its function is to enable optimal B-cell immune response, specifically against T-independent antigens. It is suspected that it acts as a calcium channel in the cell membrane. CD20 / MS4A1 is the target of the monoclonal antibodies (mAb) rituximab, Ibritumomab tiuxetan, and tositumomab, which are all active agents in the treatment of all B cell lymphomas and leukemias. Defects in CD20 / MS4A1 are the cause of immunodeficiency common variable type 5 (CVID5), also called antibody deficiency due to CD20 defect. CVID5 is a primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections and an inability to mount an antibody response to antigen.
- 分子量
- 36.9 kDa
- NCBI登录号
- NP_068769
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