CD3G Protein (AA 23-116) (Fc Tag)
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- 抗原 See all CD3G 蛋白
- CD3G (CD3g Molecule, gamma (CD3-TCR Complex) (CD3G))
- 蛋白类型
- Recombinant
- 产品特性
- AA 23-116
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This CD3G protein is labelled with Fc Tag.
- 产品特性
- Human CD3 gamma / CD3G Protein, Fc Tag (MALS verified)
- 纯度
- >95 % as determined by SDS-PAGE.
- 内毒素水平
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product CD3G 蛋白
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CD3g Molecule, gamma (CD3-TCR Complex) (CD3G) (AA 23-111) protein (GST tag)
CD3G 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
CD3g Molecule, gamma (CD3-TCR Complex) (CD3G) (AA 23-182) protein (rho-1D4 tag)Crystallography grade CD3G 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB, Crys
CD3g Molecule, gamma (CD3-TCR Complex) (CD3G) (AA 23-182) protein (rho-1D4 tag)Crystallography grade CD3G 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB, Crys
CD3g Molecule, gamma (CD3-TCR Complex) (CD3G) (AA 23-116) protein (His tag)CD3G 宿主: 人 宿主: Baculovirus infected Insect Cells Recombinant > 85 % by SDS - PAGE SDS
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- 应用备注
- MALS verified
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- PBS, pH 7.4
- 储存条件
- -20 °C
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- 抗原
- CD3G (CD3g Molecule, gamma (CD3-TCR Complex) (CD3G))
- 别名
- CD3 gamma (CD3G 产品)
- 别名
- Ctg-3 Protein, Ctg3 Protein, T3g Protein, CD3-GAMMA Protein, T3G Protein, CD3 antigen, gamma polypeptide Protein, CD3g molecule Protein, Cd3g Protein, CD3G Protein
- 背景
- CD3 gamma chain is part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of downstream signaling pathways. In addition to this role of signal transduction in T-cell activation, CD3G plays an essential role in the dynamic regulation of TCR expression at the cell surface. Indeed, constitutive TCR cycling is dependent on the di-leucine-based (diL) receptor-sorting motif present in CD3G.
- 分子量
- 37.1 kDa
- 途径
- TCR Signaling, CXCR4-mediated Signaling Events
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