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IL2RG Protein (AA 23-263) (His tag)

IL2RG 宿主: 小鼠 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE.
产品编号 ABIN6992389
发货至: 中国
  • 抗原 See all IL2RG 蛋白
    IL2RG (Interleukin 2 Receptor, gamma (IL2RG))
    蛋白类型
    Recombinant
    产品特性
    AA 23-263
    宿主
    • 18
    • 10
    • 3
    • 1
    • 1
    • 1
    小鼠
    资源
    • 14
    • 7
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    HEK-293 Cells
    标记
    This IL2RG protein is labelled with His tag.
    原理
    Mouse IL-2 R gamma / CD132 Protein, His Tag (MALS verified)
    纯度
    >90 % as determined by SDS-PAGE.
    内毒素水平
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product IL2RG 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    PBS, pH 7.4
    储存条件
    -20 °C
  • 抗原
    IL2RG (Interleukin 2 Receptor, gamma (IL2RG))
    别名
    IL-2 R gamma (IL2RG 产品)
    别名
    Ab2-183 Protein, Cd132 Protein, CD132 Protein, CIDX Protein, IL-2RG Protein, IMD4 Protein, P64 Protein, SCIDX Protein, SCIDX1 Protein, [g]c Protein, gamma(c) Protein, gc Protein, interleukin 2 receptor subunit gamma Protein, interleukin 2 receptor subunit gamma L homeolog Protein, interleukin 2 receptor, gamma chain Protein, IL2RG Protein, il2rg.L Protein, Il2rg Protein
    背景
    IL-2R is a heterotrimeric protein binds and responds to the cytokine IL-2. Three distinct chains of IL-2R, termed as α, β and γ, which are non-covalently associated are identified. The α and β chains are involved in binding IL-2, while signal transduction following cytokine interaction is carried out by the γ chain, along with the β subunit. The α chain of the IL-2R can bind to the β chain before receptor interaction with IL-2. The γ chain alone has a very weak affinity for IL-2, but after the ligand is bound to the α/β heterodimer, the γ chain becomes recruited to the complex to form a very stable macromolecular quaternary ligand/receptor complex. Interleukin-2 receptor subunit gamma (IL2RG), also known as cytokine receptor common subunit gamma, CD antigen CD132, gammaC, p64, which belongs to the type I cytokine receptor family or type 5 subfamily. IL2RG is located on the surface of immature blood-forming cells in bone marrow. Defects in IL2RG are the cause of severe combined immunodeficiency X-linked T-cell-negative/B-cell-positive/NK-cell-negative (XSCID).
    分子量
    30.1 kDa
    NCBI登录号
    NP_038591
    途径
    JAK/STAT Signaling, Growth Factor Binding
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