IL2RG Protein (AA 23-263) (His tag)
-
- 抗原 See all IL2RG 蛋白
- IL2RG (Interleukin 2 Receptor, gamma (IL2RG))
- 蛋白类型
- Recombinant
- 产品特性
- AA 23-263
-
宿主
- 小鼠
-
资源
- HEK-293 Cells
- 标记
- This IL2RG protein is labelled with His tag.
- 原理
- Mouse IL-2 R gamma / CD132 Protein, His Tag (MALS verified)
- 纯度
- >90 % as determined by SDS-PAGE.
- 内毒素水平
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product IL2RG 蛋白
-
-
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 缓冲液
- PBS, pH 7.4
- 储存条件
- -20 °C
-
- 抗原
- IL2RG (Interleukin 2 Receptor, gamma (IL2RG))
- 别名
- IL-2 R gamma (IL2RG 产品)
- 别名
- Ab2-183 Protein, Cd132 Protein, CD132 Protein, CIDX Protein, IL-2RG Protein, IMD4 Protein, P64 Protein, SCIDX Protein, SCIDX1 Protein, [g]c Protein, gamma(c) Protein, gc Protein, interleukin 2 receptor subunit gamma Protein, interleukin 2 receptor subunit gamma L homeolog Protein, interleukin 2 receptor, gamma chain Protein, IL2RG Protein, il2rg.L Protein, Il2rg Protein
- 背景
- IL-2R is a heterotrimeric protein binds and responds to the cytokine IL-2. Three distinct chains of IL-2R, termed as α, β and γ, which are non-covalently associated are identified. The α and β chains are involved in binding IL-2, while signal transduction following cytokine interaction is carried out by the γ chain, along with the β subunit. The α chain of the IL-2R can bind to the β chain before receptor interaction with IL-2. The γ chain alone has a very weak affinity for IL-2, but after the ligand is bound to the α/β heterodimer, the γ chain becomes recruited to the complex to form a very stable macromolecular quaternary ligand/receptor complex. Interleukin-2 receptor subunit gamma (IL2RG), also known as cytokine receptor common subunit gamma, CD antigen CD132, gammaC, p64, which belongs to the type I cytokine receptor family or type 5 subfamily. IL2RG is located on the surface of immature blood-forming cells in bone marrow. Defects in IL2RG are the cause of severe combined immunodeficiency X-linked T-cell-negative/B-cell-positive/NK-cell-negative (XSCID).
- 分子量
- 30.1 kDa
- NCBI登录号
- NP_038591
- 途径
- JAK/STAT Signaling, Growth Factor Binding
-