GUCY2C Protein (AA 24-430) (Fc Tag,AVI tag,Biotin)
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- 抗原 See all GUCY2C 蛋白
- GUCY2C (Guanylate Cyclase 2C (Heat Stable Enterotoxin Receptor) (GUCY2C))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 24-430
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This GUCY2C protein is labelled with Fc Tag,AVI tag,Biotin.
- 特异性
- Biotinylation of this product is performed using Avitag™ technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin.
- 产品特性
- Biotinylated Human GUCY2C / Guanylyl cyclase C Protein, Fc,Avitag™
- 纯度
- >90 % as determined by SDS-PAGE.
- 内毒素水平
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product GUCY2C 蛋白
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Guanylate Cyclase 2C (Heat Stable Enterotoxin Receptor) (GUCY2C) (AA 24-430) protein (His-Avi Tag,Biotin)
GUCY2C 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Guanylate Cyclase 2C (Heat Stable Enterotoxin Receptor) (GUCY2C) (AA 24-430) protein (Fc Tag)GUCY2C 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Guanylate Cyclase 2C (Heat Stable Enterotoxin Receptor) (GUCY2C) protein (His-Avi Tag)GUCY2C 宿主: 人 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Guanylate Cyclase 2C (Heat Stable Enterotoxin Receptor) (GUCY2C) (AA 24-430) protein (His tag)GUCY2C 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Guanylate Cyclase 2C (Heat Stable Enterotoxin Receptor) (GUCY2C) (AA 21-430) protein (His tag)GUCY2C 宿主: 犬 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Guanylate Cyclase 2C (Heat Stable Enterotoxin Receptor) (GUCY2C) (AA 24-430) (Active) protein (His tag)GUCY2C 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Guanylate Cyclase 2C (Heat Stable Enterotoxin Receptor) (GUCY2C) (AA 24-430) (Active) protein (His tag,AVI tag,Biotin)GUCY2C 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Guanylate Cyclase 2C (Heat Stable Enterotoxin Receptor) (GUCY2C) (AA 24-133) protein (GST tag)GUCY2C 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Guanylate Cyclase 2C (Heat Stable Enterotoxin Receptor) (GUCY2C) (AA 24-430) protein (His tag)Crystallography grade GUCY2C 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, Crys, SDS
Guanylate Cyclase 2C (Heat Stable Enterotoxin Receptor) (GUCY2C) (AA 20-433) protein (His tag)Crystallography grade GUCY2C 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, Crys, SDS
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- 说明
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Ready-to-use Avitag™ biotinylated protein:
The product is exclusively produced using the Avitag™ technology. Briefly, a unique 15 amino acid peptide, the Avi tag, is introduced into the recombinant protein during expression vector construction. The single lysine residue in the Avi tag is enzymatically biotinylated by the E. Coli biotin ligase BirA.
This single-point enzymatic labeling technique brings many advantages for commonly used binding assays. The biotinylation happens on the lysine residue of Avi tag, and therefore does NOT interfere with the target protein's natural binding activities. In addition, when immobilized on an avidin-coated surface, the protein orientation is uniform because the position of the Avi tag in the protein is precisely controlled. - 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- PBS, pH 7.4
- 储存条件
- -20 °C
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- 抗原
- GUCY2C (Guanylate Cyclase 2C (Heat Stable Enterotoxin Receptor) (GUCY2C))
- 别名
- GUCY2C (GUCY2C 产品)
- 别名
- DIAR6 Protein, GUC2C Protein, MECIL Protein, MUCIL Protein, STAR Protein, AI893437 Protein, GC-C Protein, Gcc Protein, GCC Protein, gucy2c-A Protein, GUCY2C Protein, Gucy2c Protein, guanylate cyclase 2C Protein, guanylate cyclase 2c Protein, guanylate cyclase 2C L homeolog Protein, GUCY2C Protein, Gucy2c Protein, gucy2c.L Protein, gucy2c Protein
- 背景
- GUCY2C (Guanylyl Cyclase C), also known as heat-stable enterotoxin receptor, is a type I transmembrane protein of the guanylate cyclase (gc) family that signal by producing cGMP. Guanylate cyclase C (GUCY2C) and its hormones guanylin and uroguanylin have recently emerged as one paracrine axis defending intestinal mucosal integrity against mutational, chemical, and inflammatory injury. GUCY2C murine CAR-T cells recognized and killed human colorectal cancer cells endogenously expressing GUCY2C. Thus, we have identified a human GUCY2C-specific CAR-T cell therapy approach that may be developed for the treatment of GUCY2C-expressing metastatic colorectal cancer.
- 分子量
- 74.1 kDa
- NCBI登录号
- NP_004954
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