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CLEC12A Protein (AA 65-265) (AVI tag,His tag,Biotin)

CLEC12A 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
产品编号 ABIN6973031
发货至: 中国
  • 抗原 See all CLEC12A 蛋白
    CLEC12A (C-Type Lectin Domain Family 12, Member A (CLEC12A))
    蛋白类型
    Recombinant
    生物活性
    Active
    产品特性
    AA 65-265
    宿主
    • 15
    • 3
    • 1
    • 1
    资源
    • 14
    • 3
    • 2
    • 1
    HEK-293 Cells
    标记
    This CLEC12A protein is labelled with AVI tag,His tag,Biotin.
    特异性
    Biotinylation of this product is performed using Avitag™ technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin.
    产品特性
    Biotinylated Human CLEC12A / MICL / CLL-1 Protein, His,Avitag™
    纯度
    >90 % as determined by SDS-PAGE.
    内毒素水平
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product CLEC12A 蛋白
  • 说明

    Ready-to-use Avitag™ biotinylated protein:
    The product is exclusively produced using the Avitag™ technology. Briefly, a unique 15 amino acid peptide, the Avi tag, is introduced into the recombinant protein during expression vector construction. The single lysine residue in the Avi tag is enzymatically biotinylated by the E. Coli biotin ligase BirA.

    This single-point enzymatic labeling technique brings many advantages for commonly used binding assays. The biotinylation happens on the lysine residue of Avi tag, and therefore does NOT interfere with the target protein's natural binding activities. In addition, when immobilized on an avidin-coated surface, the protein orientation is uniform because the position of the Avi tag in the protein is precisely controlled.

    限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    PBS, pH 7.4
    储存条件
    -20 °C
  • 抗原
    CLEC12A (C-Type Lectin Domain Family 12, Member A (CLEC12A))
    别名
    CLEC12A (CLEC12A 产品)
    别名
    MGC179455 Protein, CLL-1 Protein, CLL1 Protein, DCAL-2 Protein, MICL Protein, D230024O04 Protein, KLRL1 Protein, Micl Protein, C-type lectin domain family 12 member A Protein, C-type lectin domain family 12, member a Protein, C-type lectin domain family 12, member A Protein, CLEC12A Protein, Clec12a Protein
    背景
    CLEC12A (C-type lectin domain family 12 member A) is also known as CLL1, DCAL2, MICL. Clec12a is an inhibitory receptor for uric acid crystals that regulates inflammation in response to cell death. Cell surface receptor that modulates signaling cascades and mediates tyrosine phosphorylation of target MAP kinases. Evidence of distinct disease propagating stem cells in myelodysplastic syndrome (MDS) has emerged in recent years. The role of CLEC12A in MDS, however, remains to be elucidated. Furthermore, CLEC12A has been proposed as a promising marker of leukaemic stem cells in AML.
    分子量
    27.3 kDa
    NCBI登录号
    NP_612210
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