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IFNB1 Protein (Fc Tag)

IFNB1 宿主: 人 宿主: HEK-293 Cells Recombinant
产品编号 ABIN6964275
发货至: 中国
  • 抗原 See all IFNB1 蛋白
    IFNB1 (Interferon, beta 1, Fibroblast (IFNB1))
    蛋白类型
    Recombinant
    宿主
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    资源
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    HEK-293 Cells
    标记
    This IFNB1 protein is labelled with Fc Tag.
    序列
    IFNB(Met22-Asn187)+hFc(Glu99-Ala330)
    产品特性
    Tagged Protein: C-Human Fc tag
    纯化方法
    affinity purification
    Top Product
    Discover our top product IFNB1 蛋白
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstitute with deionized water
    缓冲液
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    储存液
    Without preservative
    储存条件
    -80 °C
    储存方法
    Store at -80°C for 12 months (Avoid repeated freezing and thawing)
    有效期
    12 months
  • 抗原
    IFNB1 (Interferon, beta 1, Fibroblast (IFNB1))
    别名
    IFNB (IFNB1 产品)
    别名
    IFB Protein, IFF Protein, IFNB Protein, IFN-beta Protein, Ifb Protein, Ifnb Protein, IFNb Protein, interferon beta 1 Protein, interferon beta 1, fibroblast Protein, interferon, beta 1, fibroblast Protein, IFNB1 Protein, Ifnb1 Protein
    背景
    Synonymes: IFB, IFF, IFN-beta, IFNB
    Description: This gene encodes a cytokine that belongs to the interferon family of signaling proteins, which are released as part of the innate immune response to pathogens. The protein encoded by this gene belongs to the type I class of interferons, which are important for defense against viral infections. In addition, type I interferons are involved in cell differentiation and anti-tumor defenses. Following secretion in response to a pathogen, type I interferons bind a homologous receptor complex and induce transcription of genes such as those encoding inflammatory cytokines and chemokines. Overactivation of type I interferon secretion is linked to autoimmune diseases. Mice deficient for this gene display several phenotypes including defects in B cell maturation and increased susceptibility to viral infection. [provided by RefSeq, Sep 2015]
    分子量
    43.6 kDa
    UniProt
    P01574
    途径
    JAK/STAT Signaling, TCR Signaling, TLR signaling, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Autophagy, Inflammasome
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