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SARS-CoV-2 Spike Protein (N501Y, RBD) (His tag)

宿主: SARS Coronavirus-2 (SARS-CoV-2) 宿主: HEK-293 Cells Recombinant
产品编号 ABIN6961041
发货至: 中国
  • 抗原 See all SARS-CoV-2 Spike 蛋白
    SARS-CoV-2 Spike
    蛋白类型
    Recombinant
    产品特性
    N501Y, RBD
    宿主
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    SARS Coronavirus-2 (SARS-CoV-2)
    资源
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    HEK-293 Cells
    标记
    This SARS-CoV-2 Spike protein is labelled with His tag.
    原理
    SARS-CoV-2 Spike Protein RBD (Mammalian, N501Y, C-6His)
    产品特性
    Recombinant 2019-nCoV S-RBD is produced by Mammalian expression system and the target gene encoding Arg319-Ser541(N501Y) is expressed with a 6His tag at the C-terminus.
    Top Product
    Discover our top product SARS-CoV-2 Spike 蛋白
  • 限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.
  • 抗原
    SARS-CoV-2 Spike
    别名
    SARS-CoV-2 S Protein (SARS-CoV-2 Spike 产品)
    别名
    E2 Protein, E2 glycoprotein precursor Protein, Surface Glycoprotein Protein, S Protein
    物质类
    Viral Protein
    背景
    The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell during the initial stages of the infection process. The SARS-CoV-2 Spike Protein mediates the membrane fusion required for virus entry and cell fusion. It is also a major immunogen and a target for entry inhibitors. SARS-CoV-2 infects the human respiratory epithelial cells through interaction with the human ACE2 receptor. The Spike Protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion. The Spike Protein plays key a part in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
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