GPC2 Protein (AA 24-553) (Fc Tag)
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- 抗原 See all GPC2 蛋白
- GPC2 (Glypican 2 (GPC2))
- 蛋白类型
- Recombinant
- 产品特性
- AA 24-553
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This GPC2 protein is labelled with Fc Tag.
- 纯度
- >95 % as determined by SDS-PAGE.
- 内毒素水平
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product GPC2 蛋白
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Glypican 2 (GPC2) (AA 22-556) protein (His tag)
GPC2 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Glypican 2 (GPC2) (AA 24-554) protein (His tag)Crystallography grade GPC2 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Glypican 2 (GPC2) (AA 22-556) protein (His tag)Crystallography grade GPC2 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Glypican 2 (GPC2) (AA 22-556) (Active) protein (His tag)GPC2 宿主: 小鼠 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Glypican 2 (GPC2) (AA 24-552) (Active) protein (His tag)GPC2 宿主: 猕猴 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Glypican 2 (GPC2) (AA 24-554) (Active) protein (His tag)GPC2 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Glypican 2 (GPC2) (AA 24-553) protein (Fc Tag)GPC2 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Tris with Glycine, Arginine and NaCl, pH 7.5
- 储存条件
- -20 °C
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- 抗原
- GPC2 (Glypican 2 (GPC2))
- 别名
- Glypican 2 (GPC2 产品)
- 别名
- 2410016G05Rik Protein, glypican 2 Protein, glypican 2 (cerebroglycan) Protein, GPC2 Protein, Gpc2 Protein
- 背景
- Glypican 2 (GPC2), also known cerebroglycan, is a glycophosphatidylinositol-linked integral membrane heparan sulfate proteoglycan found in the developing nervous system. Cerebroglycan participates in cell adhesion and is thought to regulate the growth and guidance of axons. Cerebroglycan has especially high affinity for laminin-1. GPC2 silencing inactivates Wnt/β-catenin signaling and reduces the expression of N-Myc, an oncogenic driver of neuroblastoma tumorigenesis. Immunotoxins and chimeric antigen receptor (CAR) T cells targeting GPC2 inhibit neuroblastoma growth in mouse models. A GPC3 specific antibody drug conjugate (ADC) can also inhibit neuroblastoma cell proliferation.
- 分子量
- 37.3 kDa & 47.3 kDa
- NCBI登录号
- NP_689955
- 途径
- Glycosaminoglycan Metabolic Process
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