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IGSF11 Protein (AA 23-241) (Fc Tag,AVI tag,Biotin)

IGSF11 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
产品编号 ABIN6923166
发货至: 中国
  • 抗原 See all IGSF11 蛋白
    IGSF11 (Immunoglobulin Superfamily, Member 11 (IGSF11))
    蛋白类型
    Recombinant
    生物活性
    Active
    产品特性
    AA 23-241
    宿主
    • 10
    • 4
    • 1
    • 1
    资源
    • 6
    • 4
    • 3
    • 2
    • 1
    HEK-293 Cells
    标记
    This IGSF11 protein is labelled with Fc Tag,AVI tag,Biotin.
    序列
    AA 23-241
    特异性
    Biotinylation of this product is performed using Avitag™ technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin.
    纯度
    >95 % as determined by SDS-PAGE.
    内毒素水平
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product IGSF11 蛋白
  • 说明

    Ready-to-use AvitagTM biotinylated protein:
    The product is exclusively produced using the AvitagTM technology. Briefly, a unique 15 amino acid peptide, the Avi tag, is introduced into the recombinant protein during expression vector construction. The single lysine residue in the Avi tag is enzymatically biotinylated by the E. Coli biotin ligase BirA.

    This single-point enzymatic labeling technique brings many advantages for commonly used binding assays. The biotinylation happens on the lysine residue of Avi tag, and therefore does NOT interfere with the target protein's natural binding activities. In addition, when immobilized on an avidin-coated surface, the protein orientation is uniform because the position of the Avi tag in the protein is precisely controlled.

    限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Tris with Glycine, Arginine and NaCl,  pH 7.5
    注意事项
    Please avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
  • 抗原
    IGSF11 (Immunoglobulin Superfamily, Member 11 (IGSF11))
    别名
    VSIG3 (IGSF11 产品)
    别名
    sc:d812 Protein, seurat Protein, BT-IgSF Protein, CT119 Protein, CXADRL1 Protein, Igsf13 Protein, VSIG3 Protein, 1700025L02Rik Protein, immunoglobulin superfamily member 11 Protein, immunoglobulin superfamily member 11 L homeolog Protein, immunoglobulin superfamily, member 11 Protein, IGSF11 Protein, igsf11 Protein, igsf11.L Protein, Igsf11 Protein
    背景
    VSIG3, also known as IGSF11, BT-IgSF, and CLMP, is a homophilic adhesion molecule that preferentially expressed in the brain. The function of VSIG3 is to stimulate cell growth through homophilic interactions. In clinical, the VSIG3 has been reported to as a novel target for cancer immunotherapy of gastrointestinal and hepatocellular carcinomas. In addition, VSIG-3 is also a ligand of B7 family member VISTA/PD-1H and inhibits human T-cell functions through a novel VSIG-3/VISTA pathway. VSIG-3/VISTA co-inhibitory pathway may provide new strategies for the treatment of human cancers and autoimmune disorders.
    分子量
    51.5 kDa
    NCBI登录号
    NP_001015887
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