C5 Protein (AA 19-1676) (His tag)
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- 抗原 See all C5 蛋白
- C5 (Complement Component 5 (C5))
- 蛋白类型
- Recombinant
- 产品特性
- AA 19-1676
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This C5 protein is labelled with His tag.
- 序列
- AA 19-1676
- 纯度
- >90 % as determined by SDS-PAGE.
- 内毒素水平
- Less than 1.0 EU per μg by the LAL method.
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Complement Component 5 (C5) (AA 19-1676) protein (His tag)
C5 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Complement Component 5 (C5) (AA 1550-1661) protein (GST tag)C5 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Complement Component 5 (C5) proteinC5 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by SDS-PAGE
Complement Component 5 (C5) (AA 678-751) protein (His tag)Crystallography grade C5 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Complement Component 5 (C5) (AA 679-755) protein (His tag)Crystallography grade C5 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Complement Component 5 (C5) (AA 19-673) protein (His tag)Crystallography grade C5 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Complement Component 5 (C5) (AA 19-674) protein (His tag)Crystallography grade C5 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Complement Component 5 (C5) (AA 678-1676) protein (His tag)Crystallography grade C5 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Complement Component 5 (C5) (AA 752-1676) protein (His tag)Crystallography grade C5 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Complement Component 5 (C5) (AA 679-1680) protein (His tag)Crystallography grade C5 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- PBS, pH 7.4
- 注意事项
- Please avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
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- 抗原
- C5 (Complement Component 5 (C5))
- 别名
- Complement C5 (C5 产品)
- 别名
- C5 Protein, LOC565774 Protein, C5a Protein, C5b Protein, CPAMD4 Protein, Hc Protein, RGD1561905 Protein, He Protein, complement C5 Protein, complement component 5 Protein, hemolytic complement Protein, C5 Protein, c5 Protein, Hc Protein
- 背景
- Derived from proteolytic degradation of complement C5, C5 anaphylatoxin is a mediator of local inflammatory process. C5 precursor is first processed by the removal of 4 basic residues, forming two chains, beta and alpha, linked by a disulfide bond. C5 convertase activates C5 by cleaving the alpha chain, releasing C5a anaphylatoxin and generating C5b (beta chain + alpha' chain). Activation of C5 by a C5 convertase initiates the spontaneous assembly of the late complement components, C5-C9, into the membrane attack complex. C5b has a transient binding site for C6. The C5b-C6 complex is the foundation upon which the lytic complex is assembled. The C5a anaphylatoxin interacts with C5AR1 and tick complement inhibitor. C5a is also a potent chemokine which stimulates the locomotion of polymorphonuclear leukocytes and directs their migration toward sites of inflammation.
- 分子量
- 73.9 kDa (β chain) & 114.4 kDa (α chain)
- NCBI登录号
- NP_001726
- 途径
- Complement System, Carbohydrate Homeostasis
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