ICOS Protein (AA 21-144) (His tag)
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- 抗原 See all ICOS 蛋白
- ICOS (Inducible T-Cell Co-Stimulator (ICOS))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 21-144
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宿主
- 小鼠
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资源
- HEK-293 Cells
- 标记
- This ICOS protein is labelled with His tag.
- 纯度
- >90 % as determined by SDS-PAGE.
- 内毒素水平
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product ICOS 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- PBS, pH 7.4
- 储存条件
- -20 °C
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- 抗原
- ICOS (Inducible T-Cell Co-Stimulator (ICOS))
- 别名
- ICOS (ICOS 产品)
- 别名
- ICOS Protein, AILIM Protein, CCLP Protein, CRP-1 Protein, H4 Protein, Ly115 Protein, CD278 Protein, CVID1 Protein, Ailim Protein, inducible T-cell costimulator Protein, inducible T cell co-stimulator Protein, inducible T-cell co-stimulator Protein, ICOS Protein, LOC100232284 Protein, Icos Protein
- 背景
- Inducible T-cell costimulator (ICOS) is also known as Activation-inducible lymphocyte immunomediatory molecule (AILIM), CD278, which belongs to the CD28 family of immune costimulatory receptors consisting of CD28, CTLA-4 and PD-1. ICOS enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. CD278 / ICOS prevents the apoptosis of pre-activated T-cells and also plays a critical role in CD40-mediated class switching of immunoglobin isotypes.
- 分子量
- 15.7 kDa
- 途径
- Cancer Immune Checkpoints
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