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HSD17B8 Protein (AA 1-261) (His tag)

HSD17B8 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % by SDS - PAGE SDS
产品编号 ABIN667899
发货至: 中国
  • 抗原 See all HSD17B8 蛋白
    HSD17B8 (Hydroxysteroid (17-Beta) Dehydrogenase 8 (HSD17B8))
    蛋白类型
    Recombinant
    产品特性
    AA 1-261
    宿主
    • 5
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    资源
    • 10
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    大肠杆菌(E. Coli)
    标记
    This HSD17B8 protein is labelled with His tag.
    应用范围
    SDS-PAGE (SDS)
    产品特性
    HSD17B8, 1-261aa, Human, His tag, E.coli
    纯度
    > 95 % by SDS - PAGE
    Top Product
    Discover our top product HSD17B8 蛋白
  • 限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5 mg/ml (determined by Bradford assay)
    缓冲液
    Liquid. 20mM Tris-HCl buffer (pH8.0) containing 40% glycerol, 150mM NaCl
    储存条件
    4 °C
  • 抗原
    HSD17B8 (Hydroxysteroid (17-Beta) Dehydrogenase 8 (HSD17B8))
    别名
    HSD17B8 (HSD17B8 产品)
    别名
    KE6 Protein, fabgl Protein, zgc:112550 Protein, si:dz12f11.4 Protein, HKE6 Protein, FABGL Protein, ke6 Protein, fabg Protein, hke6 Protein, ring2 Protein, h2-ke6 Protein, d6s2245e Protein, D17H6S112E Protein, H-2Ke6 Protein, Hsd17b8 Protein, Ke-6 Protein, Ke6 Protein, Ring2 Protein, D6S2245E Protein, FABG Protein, H2-KE6 Protein, RING2 Protein, SDR30C1 Protein, dJ1033B10.9 Protein, Fabgl Protein, hydroxysteroid (17-beta) dehydrogenase 8 Protein, hydroxysteroid 17-beta dehydrogenase 8 Protein, H2-K region expressed gene 6 Protein, hsd17b8 Protein, HSD17B8 Protein, H2-Ke6 Protein, Hsd17b8 Protein
    背景
    HSD17B8, also known as estradiol 17-beta-dehydrogenase 8, belongs to the short-chain dehydrogenases/reductases (SDR) family. In mice, the Ke6 protein is a 17-beta-hydroxysteroid dehydrogenase that can regulate the concentration of biologically active estrogens and androgens. It is preferentially an oxidative enzyme and inactivates estradiol, testosterone, and dihydrotestosterone. However, the enzyme has some reductive activity and can synthesize estradiol from estrone. It may play a role in biosynthesis of fatty acids in mitochondria. Recombinant human HSD17B8 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: Estradiol 17-beta-dehydrogenase 8, FABGL, HKE6, RING2. NCBI no.: NP_055049
    分子量
    29.1 kDa (281aa), confirmed by MALDI-TOF
    途径
    Steroid Hormone Biosynthesis
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