TIGAR Protein (AA 1-270) (His tag)
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- 抗原 See all TIGAR 蛋白
- TIGAR (TP53 induced glycolysis regulatory phosphatase (TIGAR))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-270
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 标记
- This TIGAR protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 产品特性
- TIGAR, 1-270aa, Human, His tag, E.coli
- 纯度
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product TIGAR 蛋白
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.5 mg/ml (determined by Bradford assay)
- 缓冲液
- Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 0.2M NaCl, 2mM DTT, 10% glycerol
- 储存条件
- 4 °C
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- 抗原
- TIGAR (TP53 induced glycolysis regulatory phosphatase (TIGAR))
- 别名
- TIGAR (TIGAR 产品)
- 别名
- AA793651 Protein, AI595337 Protein, C79710 Protein, C85509 Protein, Tigar Protein, Trp53 induced glycolysis repulatory phosphatase Protein, Tigar Protein
- 背景
- TIGAR, also known as TP53-induced glycolysis and apoptosis regulator, is a 270 amino acid protein induced by the p53 tumor suppressor pathway that functions to protect against oxidative stress. TIGAR specifically functions to block glycolysis, leading the pathway to the pentose phosphate shunt and decreasing the intracellular concentration of reactive oxygen species. These facts indicate that TIGAR may act to modulate the apoptotic response to p53, thereby allowing cells to survive mild or transient stresses. Recombinant human TIGAR protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: TP53-induced glycolysis and apoptosis regulator,. NCBI no.: NP_065108
- 分子量
- 32.6 kDa (294aa), confirmed by MALDI-TOF
- 途径
- Warburg Effect
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