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TIGAR Protein (AA 1-270) (His tag)

TIGAR 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % by SDS - PAGE SDS
产品编号 ABIN7279263
发货至: 中国
  • 抗原 See all TIGAR 蛋白
    TIGAR (TP53 induced glycolysis regulatory phosphatase (TIGAR))
    蛋白类型
    Recombinant
    产品特性
    AA 1-270
    宿主
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    资源
    • 5
    • 3
    • 2
    • 1
    • 1
    大肠杆菌(E. Coli)
    标记
    This TIGAR protein is labelled with His tag.
    应用范围
    SDS-PAGE (SDS)
    产品特性
    TIGAR, 1-270aa, Human, His tag, E.coli
    纯度
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product TIGAR 蛋白
  • 限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5 mg/ml (determined by Bradford assay)
    缓冲液
    Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 0.2M NaCl, 2mM DTT, 10% glycerol
    储存条件
    4 °C
  • 抗原
    TIGAR (TP53 induced glycolysis regulatory phosphatase (TIGAR))
    别名
    TIGAR (TIGAR 产品)
    别名
    AA793651 Protein, AI595337 Protein, C79710 Protein, C85509 Protein, Tigar Protein, Trp53 induced glycolysis repulatory phosphatase Protein, Tigar Protein
    背景
    TIGAR, also known as TP53-induced glycolysis and apoptosis regulator, is a 270 amino acid protein induced by the p53 tumor suppressor pathway that functions to protect against oxidative stress. TIGAR specifically functions to block glycolysis, leading the pathway to the pentose phosphate shunt and decreasing the intracellular concentration of reactive oxygen species. These facts indicate that TIGAR may act to modulate the apoptotic response to p53, thereby allowing cells to survive mild or transient stresses. Recombinant human TIGAR protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: TP53-induced glycolysis and apoptosis regulator,. NCBI no.: NP_065108
    分子量
    32.6 kDa (294aa), confirmed by MALDI-TOF
    途径
    Warburg Effect
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