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ITPA Protein (AA 1-194) (His tag)

ITPA 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % by SDS - PAGE SDS
产品编号 ABIN667158
发货至: 中国
  • 抗原 See all ITPA 蛋白
    ITPA (Inosine Triphosphatase (ITPA))
    蛋白类型
    Recombinant
    产品特性
    AA 1-194
    宿主
    • 9
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    资源
    • 7
    • 6
    • 2
    • 2
    • 1
    大肠杆菌(E. Coli)
    标记
    This ITPA protein is labelled with His tag.
    应用范围
    SDS-PAGE (SDS)
    产品特性
    ITPA, 1-194aa, Human, His tag, E.coli
    纯度
    > 95 % by SDS - PAGE
    Top Product
    Discover our top product ITPA 蛋白
  • 限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1.0 mg/ml (determined by Bradford assay)
    缓冲液
    Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol
    储存条件
    4 °C
  • 抗原
    ITPA (Inosine Triphosphatase (ITPA))
    别名
    ITPA (ITPA 产品)
    别名
    DDBDRAFT_0215619 Protein, DDBDRAFT_0238062 Protein, DDB_0215619 Protein, DDB_0238062 Protein, 2010016I08Rik Protein, AU020102 Protein, Itp Protein, C20orf37 Protein, HLC14-06-P Protein, dJ794I6.3 Protein, ITPase Protein, NTPase Protein, si:ch73-18j6.1 Protein, si:dkey-19f21.1 Protein, inosine triphosphatase Protein, inosine triphosphatase (nucleoside triphosphate pyrophosphatase) Protein, Inosine triphosphate pyrophosphatase Protein, inosine triphosphatase S homeolog Protein, itpa Protein, ITPA Protein, LOC733043 Protein, Itpa Protein, pco148511 Protein, itpa.S Protein
    背景
    ITPA, also known as Inosine triphosphate pyrophosphatase, is an enzyme that catalyzes the pyrophosphohydrolysis of both ITP (inosine triphosphate) and dITP (deoxyinosine triphosphate) to IMP (inosine monophosphate) and diphosphate. IMP can be used as a substrate for purine nucleotide pathways. IMP can be phosphorylated to ITP, and ITPA can regulate the concentration of ITP in the cell by converting ITP back to IMP. Defects in ITPA result in ITPA deficiency which is thought to be inherited and is characterized by an over-accumulation of ITP in erythocytes, leukocytes and fibroblasts. Recombinant human ITPA protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: C20orf37, dJ794I6.3, HLC14-06-P, ITPase, My049, OK/SW-cl.9, Inosine triphosphate pyrophosphatase. NCBI no.: NP_258412
    分子量
    23.7kDa (215aa) confirmed by MALDI-TOF
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