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TYMS Protein (AA 1-313) (His tag)

TYMS 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % by SDS - PAGE SDS
产品编号 ABIN666924
发货至: 中国
  • 抗原 See all TYMS 蛋白
    TYMS (Thymidylate Synthetase (TYMS))
    蛋白类型
    Recombinant
    产品特性
    AA 1-313
    宿主
    • 7
    • 1
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    • 1
    资源
    • 4
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    大肠杆菌(E. Coli)
    标记
    This TYMS protein is labelled with His tag.
    应用范围
    SDS-PAGE (SDS)
    产品特性
    Thymidylate synthase, 1-313aa, Human, His tag, E.coli
    纯度
    > 95 % by SDS - PAGE
    Top Product
    Discover our top product TYMS 蛋白
  • 限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/ml (determined by Bradford assay)
    缓冲液
    Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 1mM DTT, 0.1 M NaCl.
    储存条件
    4 °C
  • 抗原
    TYMS (Thymidylate Synthetase (TYMS))
    别名
    Thymidylate synthase (TYMS 产品)
    别名
    FN1 Protein, ECK2823 Protein, JW2795 Protein, ts Protein, Ts Protein, HST422 Protein, TMS Protein, TS Protein, thymidylate synthetase Protein, contains intron in T4 phage Protein, ThyE Protein, thymidylate synthase Protein, thymidylate synthetase L homeolog Protein, TYMS Protein, thyA Protein, td Protein, thyE Protein, DDA3937_RS04960 Protein, tyms.L Protein, XBJ1_RS15770 Protein, EAMY_RS20680 Protein, Tyms Protein
    物质类
    Viral Protein
    背景
    Thymidylate synthase is an intracellular enzyme critical for de novo synthesis of DNA. This function maintains the dTMP(thymidine-5-prime monophosphate) pool critical for DNA replication and repair. In cancer, expression of this protein is often elevated and becomes further elevated as a result of treatment with the most commonly used chemotherapeutic, 5-fluorouracil (5-FU). Resistance or lack of response to 5-FU is attributed to the elevation of thymidylate synthase activity. Recombinant human Thymidylate synthase protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: HST422, TMS, TS, d TMP synthase, EC 2.1.1.45, MGC88736, Thymidylate synthase, Thymidylate synthetase, Tsase, TYMS, TYMS protein, Tyms thymidylate synthetase,. NCBI no.: NP_001062
    分子量
    37.8 kDa (333aa), confirmed by MALDI-TOF.
    途径
    Mitotic G1-G1/S Phases
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