MGMT Protein (AA 1-207) (His tag)
-
- 抗原 See all MGMT 蛋白
- MGMT (O6-Methylguanine-DNA-Methyltransferase (MGMT))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-207
-
宿主
- 人
-
资源
- 大肠杆菌(E. Coli)
- 标记
- This MGMT protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 产品特性
- MGMT, 1-207aa, Human, His-tagged, Recombinant, E.coli
- 纯度
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product MGMT 蛋白
-
-
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 0.5 mg/ml (determined by Bradford assay)
- 缓冲液
- Liquid. In 20 mM Tris-HCl buffer (pH 7.5) containing 1 mM DTT, 10% glycerol
- 储存条件
- 4 °C
-
- 抗原
- MGMT (O6-Methylguanine-DNA-Methyltransferase (MGMT))
- 别名
- MGMT (MGMT 产品)
- 别名
- AGT Protein, AI267024 Protein, Agat Protein, O-6-methylguanine-DNA methyltransferase Protein, MGMT Protein, Mgmt Protein
- 背景
- O-6-methylguanine-DNA methyltransferase (MGMT) is an enzyme that repairs O-6-methylguanine, a mutagenic DNA base damaged by endogenous and environmental alkylating agents and is involved in the cellular defense against the biological effects of O-6-methylguanine in DNA. MGMT repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. There are few reports that abnormal MGMT expression correlates with the prognosis in human solid cancers. Recombinant MGMT, fused to His-tag at N-terminus, was expressed in E.coli and was purified by conventional chromatography techniques. Synonyms: O-6-methylguanine-DNA methyltransferase, MGMT, EC 2.1.1.63, O-6-methylguanine-DNA-alkyltransferase, O-6-methylguanine-DNA methyltransferase 6 O methylguanine DNA methyltransferase, Agat, AGT, AI267024, MGC107020, Methylated DNA protein cysteine methyltransferase, Methylguanine DNA methyltransferase, O 6 methylguanine DNA alkyltransferase. NCBI no.: NP_002403
- 分子量
- 23.8 kDa (227 aa), confirmed by MALDI-TOF. (Molecular weight on SDS-PAGE will appear higher)
- 途径
- DNA Damage Repair, Positive Regulation of Response to DNA Damage Stimulus
-