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RFXANK Protein (AA 1-237) (His tag)

RFXANK 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 85 % by SDS - PAGE SDS
产品编号 ABIN6387233
发货至: 中国
  • 抗原 See all RFXANK 蛋白
    RFXANK (Regulatory Factor X-Associated Ankyrin Containing Protein (RFXANK))
    蛋白类型
    Recombinant
    产品特性
    AA 1-237
    宿主
    • 5
    • 1
    资源
    • 2
    • 2
    • 1
    • 1
    大肠杆菌(E. Coli)
    标记
    This RFXANK protein is labelled with His tag.
    应用范围
    SDS-PAGE (SDS)
    序列
    MGSSHHHHHH SSGLVPRGSH MGSMELTQPA EDLIQTQQTP ASELGDPEDP GEEAADGSDT VVLSLFPCTP EPVNPEPDAS VSSPQGSSLK HSTTLTNRQR GNEVSALPAT LDCDNLVNKP DERGFTPLIW ASAFGEIETV RFLLEWGADP HILAKERESA LSLASTGGYT DIVGLLLERD VDINIYDWNG GTPLLYAVRG NHVKCVEALL ARGADLTTEA DSGYTPMDLA VALGYRKVQQ VIENHILKLF QSNLVPADPE
    纯度
    > 85 % by SDS - PAGE
    Top Product
    Discover our top product RFXANK 蛋白
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    缓冲液
    Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 0.15M NaCl, 20 % glycerol.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
  • 抗原
    RFXANK (Regulatory Factor X-Associated Ankyrin Containing Protein (RFXANK))
    别名
    RFXANK (RFXANK 产品)
    别名
    ANKRA1 Protein, BLS Protein, F14150_1 Protein, RFX-B Protein, Tvl1 Protein, regulatory factor X associated ankyrin containing protein Protein, regulatory factor X-associated ankyrin-containing protein Protein, RFXANK Protein, Rfxank Protein
    背景
    RFXANK, along with regulatory factor X-associated protein and regulatory factor-5, forms a complex that binds to the X box motif of certain MHC class II gene promoters and activates their transcription. Once bound to the promoter, this complex associates with the non-DNA-binding factor MHC class II transactivator, which controls the cell type specificity and inducibility of MHC class II gene expression. This protein contains ankyrin repeats involved in protein-protein interactions. Mutations in this gene have been linked to bare lymphocyte syndrome type II, complementation group B. Two transcript variants encoding different isoforms have been described for this gene, with only one isoform showing activation activity. Recombinant human RFXANK protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
    分子量
    28 kDa (260aa), confirmed by MALDI-TOF
    NCBI登录号
    NP_604389
    UniProt
    O14593
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