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BCL10 Protein (His tag)

BCL10 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 85 % by SDS - PAGE SDS
产品编号 ABIN7279750
发货至: 中国
  • 抗原 See all BCL10 蛋白
    BCL10 (B-Cell CLL/lymphoma 10 (BCL10))
    蛋白类型
    Recombinant
    宿主
    • 4
    • 2
    • 1
    资源
    • 3
    • 1
    • 1
    • 1
    • 1
    大肠杆菌(E. Coli)
    标记
    This BCL10 protein is labelled with His tag.
    应用范围
    SDS-PAGE (SDS)
    纯化方法
    purified by using conventional chromatography.
    纯度
    > 85 % by SDS - PAGE
    Top Product
    Discover our top product BCL10 蛋白
  • 说明

    Synonyms: B-cell lymphoma/leukemia 10, c-E10, CARMEN, CIPER, CLAP, mE10

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5 mg/ml (determined by Bradford assay)
    缓冲液
    20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.05 M NaCl, 1 MM DTT
    储存条件
    4 °C
    储存方法
    Avoid repeated freezing and thawing cycles.
  • 抗原
    BCL10 (B-Cell CLL/lymphoma 10 (BCL10))
    别名
    BCL10 (BCL10 产品)
    别名
    CARMEN Protein, CIPER Protein, CLAP Protein, c-E10 Protein, mE10 Protein, BCL10 Protein, AI132454 Protein, BCL-10 Protein, C81403 Protein, ME10 Protein, cE10 Protein, bcl10 Protein, B-cell CLL/lymphoma 10 Protein, B-cell lymphoma/leukemia 10-like Protein, B cell leukemia/lymphoma 10 Protein, B-cell lymphoma/leukemia 10 Protein, BCL10 Protein, Bcl10 Protein, bcl10 Protein, LOC100223183 Protein
    背景
    BCL10, also known as B-cell lymphoma/leukemia 10, contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. It is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and this protein are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy. Recombinant human BCL10 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
    分子量
    28.8 kDa (257aa) confirmed by MALDI-TOF (molecular weight on SDS-PAGE will appear higher)
    NCBI登录号
    NP_003912
    途径
    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Positive Regulation of Endopeptidase Activity, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteins
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