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NKIRAS1 Protein (AA 1-192) (His tag)

NKIRAS1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % by SDS - PAGE SDS
产品编号 ABIN6386901
发货至: 中国
  • 抗原 See all NKIRAS1 蛋白
    NKIRAS1 (NFKB Inhibitor Interacting Ras-Like 1 (NKIRAS1))
    蛋白类型
    Recombinant
    产品特性
    AA 1-192
    宿主
    • 3
    • 1
    • 1
    • 1
    资源
    • 2
    • 1
    • 1
    • 1
    • 1
    大肠杆菌(E. Coli)
    标记
    This NKIRAS1 protein is labelled with His tag.
    应用范围
    SDS-PAGE (SDS)
    产品特性
    NKIRAS1, 1-192aa , Human, His tag, E.coli
    纯度
    > 95 % by SDS - PAGE
    Top Product
    Discover our top product NKIRAS1 蛋白
  • 限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/ml (determined by Bradford assay)
    缓冲液
    Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 1mM DTT
    储存条件
    4 °C
  • 抗原
    NKIRAS1 (NFKB Inhibitor Interacting Ras-Like 1 (NKIRAS1))
    别名
    NKIRAS1 (NKIRAS1 产品)
    别名
    NKIRAS1 Protein, KBRAS1 Protein, kappaB-Ras1 Protein, zgc:92823 Protein, kbras1 Protein, 2400004O09Rik Protein, NFKB inhibitor interacting Ras like 1 Protein, NFKB inhibitor interacting Ras-like 1 Protein, NFKB inhibitor interacting Ras-like 1 S homeolog Protein, NFKB inhibitor interacting Ras-like protein 1 Protein, NKIRAS1 Protein, nkiras1 Protein, nkiras1.S Protein, Nkiras1 Protein
    背景
    NKIRAS1, also known as NF-kappa-B inhibitor-interacting Ras-like protein 1, belongs to the small GTPase superfamily. NKIRAS1 is atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. It may act by blocking phosphorylation of NFKBIB and mediating cytoplasmic retention of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB. Recombinant human NKIRAS1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: NF-kappa-B inhibitor-interacting Ras-like protein 1, kappaB-Ras1, KBRAS1. NCBI no.: NP_065078
    分子量
    23.8 kDa (212aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
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