N-acetyltransferase, also known as FUS2 (NAT6), is an enzyme that catalyzes the transfer of acetyl groups from acetyl-CoA to acrylamines. This enzyme is physically localized in the cytoplasm and its activity has been documented by its feasibility to acetylate the N-terminus of proteins using a ping-pong-like mechanism and by its substrate specificity. Since the Fus-2 gene maps to the chromosomal region 3p21.3, which contains at least one tumor suppressor gene, the N-acetyltransferase functions of Fus-2 may be relevant to its potential role in cancer. Recombinant human N-acetyltransferase 6 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: Protein fusion-2, FUS2, FUS-2, NAT6, FUS 2, N acetyltransferase 6, Protein fus 2, Protein fusion 2. NCBI no.: NP_036323
分子量
35.9 kDa (328aa), confirmed by MALDI-TOF. (Molecular weight on SDS-PAGE will appear higher)