CD83 Protein (CD83) (AA 22-135) (Fc Tag)
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- 抗原 See all CD83 蛋白
- CD83
- 蛋白类型
- Recombinant
- 产品特性
- AA 22-135
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宿主
- 小鼠
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资源
- CHO Cells
- 标记
- This CD83 protein is labelled with Fc Tag.
- 原理
- CD83 (mouse):Fc (mouse) (rec.)
- 特异性
- The extracellular domain of mouse CD83 (aa 22-135) is fused to the N-terminus of the Fc region of mouse IgG2a.
- 产品特性
- Protein. The extracellular domain of mouse CD83 (aa 22-135) is fused to the N-terminus of the Fc region of mouse IgG2a. Source: CHO cells. Endotoxin content: <0.06EU/μg protein (LAL test, Lonza). Lyophilized from 0.2μm-filtered solution in PBS. Purity: >98 % (SDS-PAGE). Mouse CD83 is a 30-35 kDa member of the Siglec (or sialic-acid-binding immunoglobulin-like lectin) family of transmembrane proteins. CD83 is a primary marker for dendritic cells. It is also found on B cells, neutrophils, monocytes and macrophages. Except for dendritic cells, CD83 expression is often transient. CD83 binds to sialic acids on target cells. Membrane CD83 promotes T cell proliferation, particularly of CD8+ cytotoxic T cells. Soluble CD83 is immunosuppressive and blocks T cell activation. On monocytes, CD83 is suggested to drive monocytes into a fibrocyte phenotype. A lack of membrane-expressed CD83 leads to an unusual IL-4/ IL-10 producing CD4+ T cell phenotype.
- 纯度
- >98 % (SDS-PAGE)
- 内毒素水平
- <0.06EU/μg protein (LAL test, Lonza).
- Top Product
- Discover our top product CD83 蛋白
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CD83 (CD83) (AA 20-143) protein (Fc Tag)
CD83 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD83 (CD83) (AA 20-143) protein (His tag)CD83 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD83 (CD83) (AA 20-147) protein (His tag)CD83 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD83 (CD83) (AA 22-134) protein (Fc Tag)CD83 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD83 (CD83) (AA 22-134) protein (His tag)CD83 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE
CD83 (CD83) (AA 1-205) protein (GST tag)CD83 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
CD83 (CD83) protein (His tag)CD83 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE
CD83 (CD83) (AA 1-133) protein (His tag)CD83 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE
CD83 (CD83) protein (Fc Tag)CD83 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 76 % as determined by SDS-PAGE
CD83 (CD83) (AA 20-144) protein (His tag)Crystallography grade CD83 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 浓度
- Lot specific
- 缓冲液
- Lyophilized from 0.2μm-filtered solution in PBS.
- 注意事项
- Avoid freeze/thaw cycles.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Short Term Storage: +4°C
Long Term Storage: -20°C
Use & Stability: Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
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- 抗原
- CD83
- 别名
- CD83 (CD83 产品)
- 别名
- BL11 Protein, HB15 Protein, CD83 molecule Protein, CD83 antigen Protein, Cd83 Protein, CD83 Protein
- 背景
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Product Description: Mouse CD83 is a 30-35 kDa member of the Siglec (or sialic-acid-binding immunoglobulin-like lectin) family of transmembrane proteins. CD83 is a primary marker for dendritic cells. It is also found on B cells, neutrophils, monocytes and macrophages. Except for dendritic cells, CD83 expression is often transient. CD83 binds to sialic acids on target cells. Membrane CD83 promotes T cell proliferation, particularly of CD8+ cytotoxic T cells. Soluble CD83 is immunosuppressive and blocks T cell activation. On monocytes, CD83 is suggested to drive monocytes into a fibrocyte phenotype. A lack of membrane-expressed CD83 leads to an unusual IL-4/ IL-10 producing CD4+ T cell phenotype.
- NCBI登录号
- NP_033986
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