LTBR Protein (AA 31-225) (Fc Tag)
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- 抗原 See all LTBR 蛋白
- LTBR (Lymphotoxin beta Receptor (TNFR Superfamily, Member 3) (LTBR))
- 蛋白类型
- Recombinant
- 产品特性
- AA 31-225
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宿主
- 人
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资源
- CHO Cells
- 标记
- This LTBR protein is labelled with Fc Tag.
- 原理
- LTbetaR (human):Fc (human) (rec.) (non-lytic)
- 特异性
- The extracellular domain of human LTbetaR (aa 31-225) is fused to the N-terminus of the Fc region of a mutant human IgG1.
- 产品特性
- Protein. The extracellular domain of human LTbetaR (aa 31-225) is fused to the N-terminus of the Fc region of a mutant human IgG1. Source: CHO cells. Endotoxin content: <0.06EU/μg protein (LAL test, Lonza). Lyophilized from 0.2μm-filtered solution in PBS. Purity: >98 % (SDS-PAGE). The LTbetaR activates two different NF-kappaB pathways that lead to distinct patterns of gene induction, including selected chemokines, and the cytokine BAFF, which is essential for the survival of mature B lymphocytes. LTbetaR activates the classical NF-kappaB (relA/p50) pathway, like the type 1 TNF receptor (TNFR1), that regulates proinflammatory genes, like the chemokine MIP1beta. However, LTbetaR, unlike TNFR1, also activates the processing of p100 to form RelB/p52 complexes, which activate genes involved in lymphoid organ formation and lymphocyte survival.
- 纯度
- >98 % (SDS-PAGE)
- 内毒素水平
- <0.06EU/μg protein (LAL test, Lonza).
- Biological Activity Comment
- Shows the biological function of the LTbetaR moiety and exerts a prolonged circulating half-life caused by the modified Fc domain.
- Top Product
- Discover our top product LTBR 蛋白
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Lymphotoxin beta Receptor (TNFR Superfamily, Member 3) (LTBR) (AA 31-227) protein (Fc Tag)
LTBR 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Lymphotoxin beta Receptor (TNFR Superfamily, Member 3) (LTBR) (AA 31-223) protein (Fc Tag)LTBR 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Lymphotoxin beta Receptor (TNFR Superfamily, Member 3) (LTBR) (AA 31-435) protein (GST tag)LTBR 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Lymphotoxin beta Receptor (TNFR Superfamily, Member 3) (LTBR) protein (Fc Tag)LTBR 宿主: 大鼠 宿主: HEK-293 Cells Recombinant (9.8+79.7) % as determined by SDS-PAGE
Lymphotoxin beta Receptor (TNFR Superfamily, Member 3) (LTBR) protein (His tag)LTBR 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 96 % as determined by SDS-PAGE
Lymphotoxin beta Receptor (TNFR Superfamily, Member 3) (LTBR) (AA 249-435) protein (His tag)Crystallography grade LTBR 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Lymphotoxin beta Receptor (TNFR Superfamily, Member 3) (LTBR) (AA 31-227) protein (His tag)Crystallography grade LTBR 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Lymphotoxin beta Receptor (TNFR Superfamily, Member 3) (LTBR) (AA 245-415) protein (His tag)Crystallography grade LTBR 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Lymphotoxin beta Receptor (TNFR Superfamily, Member 3) (LTBR) (AA 31-223) protein (His tag)Crystallography grade LTBR 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Lymphotoxin beta Receptor (TNFR Superfamily, Member 3) (LTBR) (AA 31-435) protein (rho-1D4 tag)Crystallography grade LTBR 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 浓度
- Lot specific
- 缓冲液
- Lyophilized from 0.2μm-filtered solution in PBS.
- 注意事项
- Avoid freeze/thaw cycles.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Short Term Storage: +4°C
Long Term Storage: -20°C
Use & Stability: Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
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- 抗原
- LTBR (Lymphotoxin beta Receptor (TNFR Superfamily, Member 3) (LTBR))
- 别名
- LTbetaR (LTBR 产品)
- 别名
- AI256028 Protein, CD18 Protein, LTbetaR Protein, Ltar Protein, TNF-R-III Protein, TNFCR Protein, TNFR-RP Protein, TNFR2-RP Protein, TNFRrp Protein, Tnfbr Protein, Tnfrsf3 Protein, D12S370 Protein, LT-BETA-R Protein, TNFR3 Protein, TNFRSF3 Protein, lymphotoxin beta receptor Protein, lymphotoxin B receptor Protein, Ltbr Protein, LTBR Protein
- 背景
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Alternate Names/Synonyms: Lymphotoxin-beta Receptor, Tumor Necrosis Factor Receptor 2 Related Protein, Tumor Necrosis Factor C Receptor, Tumor Necrosis Factor Receptor Superfamily Member 3, TNFRSF3
Product Description: The LTbetaR activates two different NF-kappaB pathways that lead to distinct patterns of gene induction, including selected chemokines, and the cytokine BAFF, which is essential for the survival of mature B lymphocytes. LTbetaR activates the classical NF-kappaB (relA/p50) pathway, like the type 1 TNF receptor (TNFR1), that regulates proinflammatory genes, like the chemokine MIP1beta. However, LTbetaR, unlike TNFR1, also activates the processing of p100 to form RelB/p52 complexes, which activate genes involved in lymphoid organ formation and lymphocyte survival.
- NCBI登录号
- NP_002333
- 途径
- NF-kappaB Signaling
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