CCL20 Protein (AA 27-96) (Fc Tag)
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- 抗原 See all CCL20 蛋白
- CCL20 (Chemokine (C-C Motif) Ligand 20 (CCL20))
- 蛋白类型
- Recombinant
- 产品特性
- AA 27-96
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This CCL20 protein is labelled with Fc Tag.
- 原理
- CCL20 (human):Fc (human) (rec.)
- 特异性
- The extracellular domain of human CCL20 (aa 27-96) is fused to the N-terminus of the Fc region of human IgG1.
- 产品特性
- Protein. The extracellular domain of human CCL20 (aa 27-96) is fused to the N-terminus of the Fc region of human IgG1. Source: HEK 293 cells. Endotoxin content: <5EU/mg protein (LAL test, Lonza). Lyophilized from 0.2μm-filtered solution in PBS. Purity: >95 % (SDS-PAGE). Macrophage Inflammatory Protein-3 (MIP3A) or Chemokine (C-C motif) ligand 20 (CCL20) or liver activation regulated chemokine (LARC) or is a small cytokine belonging to the CC chemokine family that attracts immature dendritic cells and memory T lymphocytes, both expressing CCR6. Depending on the cell type, this chemokine was found to be inducible by cytokines (IL-1beta) and by bacterial, viral, or plant products. MIP3A / CCL20 is Expressed predominantly in the liver, lymph nodes, appendix, peripheral blood lymphocytes, and fetal lung. Low levels of MIP3A / CCL20 has been seen in thymus, prostate, testis, small intestine and colon. As a chemotactic factor, MIP3A / CCL20 attracts lymphocytes and, slightly, neutrophils, but not monocytes. This chemokine may Inhibit proliferation of myeloid progenitors in colony formation assays and it may be involved in formation and function of the mucosal lymphoid tissues by attracting lymphocytes and dendritic cells towards epithelial cells. Its C-terminal processed forms have been shown to be equally chemotactically active for leukocytes. Deregulation of miRNAs and chemokine CCL20 was shown to play a role in colorectal cancer (CRC) pathogenesis and the regulation of CCL20 expression by miR-21 might be a regulatory mechanism involved in progression of colorectal cancer (CRC).
- 纯度
- >95 % (SDS-PAGE)
- 内毒素水平
- <5EU/mg protein (LAL test, Lonza).
- Top Product
- Discover our top product CCL20 蛋白
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Chemokine (C-C Motif) Ligand 20 (CCL20) (AA 27-96) protein (His tag)
CCL20 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by Tris-Bis PAGE
Chemokine (C-C Motif) Ligand 20 (CCL20) protein (His tag)CCL20 宿主: 人 宿主: 人细胞 Recombinant >95 % as determined by reducing SDS-PAGE.
Chemokine (C-C Motif) Ligand 20 (CCL20) (AA 27-95) protein (GST tag)CCL20 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Chemokine (C-C Motif) Ligand 20 (CCL20) (AA 27-90) protein (His tag)Crystallography grade CCL20 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Chemokine (C-C Motif) Ligand 20 (CCL20) (AA 27-93) protein (His tag)Crystallography grade CCL20 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Chemokine (C-C Motif) Ligand 20 (CCL20) (AA 28-96) protein (His tag)Crystallography grade CCL20 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Chemokine (C-C Motif) Ligand 20 (CCL20) (AA 28-97) protein (His tag)Crystallography grade CCL20 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 浓度
- Lot specific
- 缓冲液
- Lyophilized from 0.2μm-filtered solution in PBS.
- 注意事项
- Avoid freeze/thaw cycles.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Short Term Storage: +4°C
Long Term Storage: -20°C
Use & Stability: Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
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- 抗原
- CCL20 (Chemokine (C-C Motif) Ligand 20 (CCL20))
- 别名
- CCL20 (CCL20 产品)
- 别名
- MIP-3ALPHA Protein, CCL20 Protein, si:dkey-150o13.1 Protein, CKb4 Protein, LARC Protein, MIP-3-alpha Protein, MIP-3a Protein, MIP3A Protein, SCYA20 Protein, ST38 Protein, MIP-3A Protein, MIP-3[a] Protein, Scya20 Protein, exodus-1 Protein, C-C motif chemokine ligand 20 Protein, chemokine (C-C motif) ligand 20b Protein, chemokine (C-C motif) ligand 20 Protein, CCL20 Protein, ccl20b Protein, Ccl20 Protein
- 背景
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Alternate Names/Synonyms: Chemokine (C-C motif) ligand 20, LARC, MIP-3A, ST38, Scya20, Exodus-1
Product Description: Macrophage Inflammatory Protein-3 (MIP3A) or Chemokine (C-C motif) ligand 20 (CCL20) or liver activation regulated chemokine (LARC) or is a small cytokine belonging to the CC chemokine family that attracts immature dendritic cells and memory T lymphocytes, both expressing CCR6. Depending on the cell type, this chemokine was found to be inducible by cytokines (IL-1beta) and by bacterial, viral, or plant products. MIP3A / CCL20 is Expressed predominantly in the liver, lymph nodes, appendix, peripheral blood lymphocytes, and fetal lung. Low levels of MIP3A / CCL20 has been seen in thymus, prostate, testis, small intestine and colon. As a chemotactic factor, MIP3A / CCL20 attracts lymphocytes and, slightly, neutrophils, but not monocytes. This chemokine may Inhibit proliferation of myeloid progenitors in colony formation assays and it may be involved in formation and function of the mucosal lymphoid tissues by attracting lymphocytes and dendritic cells towards epithelial cells. Its C-terminal processed forms have been shown to be equally chemotactically active for leukocytes. Deregulation of miRNAs and chemokine CCL20 was shown to play a role in colorectal cancer (CRC) pathogenesis and the regulation of CCL20 expression by miR-21 might be a regulatory mechanism involved in progression of colorectal cancer (CRC).
- 分子量
- ~38kDa (SDS-PAGE)
- 途径
- The Global Phosphorylation Landscape of SARS-CoV-2 Infection
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