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IL-10 Protein (AA 1-178) (Fc Tag)

IL10 宿主: 小鼠 宿主: CHO Cells Recombinant >98 % (SDS-PAGE)
产品编号 ABIN7278731
发货至: 中国
  • 抗原 See all IL-10 (IL10) 蛋白
    IL-10 (IL10) (Interleukin 10 (IL10))
    蛋白类型
    Recombinant
    产品特性
    AA 1-178
    宿主
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    小鼠
    资源
    • 32
    • 22
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    CHO Cells
    标记
    This IL-10 protein is labelled with Fc Tag.
    原理
    IL-10 (mouse):Fc (mouse) (rec.) (non-lytic)
    特异性
    The extracellular domain of mouse IL-10 (aa 1-178) is fused to the N-terminus of the Fc region of a mutant mouse IgG2a.
    产品特性
    Protein. The extracellular domain of mouse IL-10 (aa 1-178) is fused to the N-terminus of the Fc region of a mutant mouse IgG2a. Source: CHO cells. Endotoxin content: <0.06EU/μg protein (LAL test, Lonza). Lyophilized from 0.2μm-filtered solution in PBS. Purity: >98 % (SDS-PAGE). Interleukin-10 (IL-10) is a cytokine produced by activated Th2 cells, B cells, keratinocytes and monocytes/macrophages. In vitro murine and human IL-10 inhibits cytokine synthesis by Th1 cells, natural killer cells and monocytes/macrophages. Several studies have suggested the potential application of IL-10 as an anti-inflammatory agent in the treatment of septic shock and as an immunosuppressive agent in certain T cell mediated autoimmune diseases.
    纯度
    >98 % (SDS-PAGE)
    内毒素水平
    <0.06EU/μg protein (LAL test, Lonza).
    Biological Activity Comment
    Shows the biological function of the IL-10 moiety and exerts a prolonged circulating half-life caused by the modified Fc domain.
    Top Product
    Discover our top product IL10 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    浓度
    Lot specific
    缓冲液
    Lyophilized from 0.2μm-filtered solution in PBS.
    注意事项
    Avoid freeze/thaw cycles.
    储存条件
    4 °C,-20 °C
    储存方法

    Short Term Storage: +4°C

    Long Term Storage: -20°C

    Use & Stability: Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.

  • 抗原
    IL-10 (IL10) (Interleukin 10 (IL10))
    别名
    IL-10 (IL10 产品)
    别名
    CSIF Protein, GVHDS Protein, IL-10 Protein, IL10A Protein, TGIF Protein, Il-10 Protein, IL10X Protein, interleukin 10 Protein, IL10 Protein, Il10 Protein
    背景

    Alternate Names/Synonyms: Interleukin-10, Cytokine Sythesis Inhibitory Factor, CSIF

    Product Description: Interleukin-10 (IL-10) is a cytokine produced by activated Th2 cells, B cells, keratinocytes and monocytes/macrophages. In vitro murine and human IL-10 inhibits cytokine synthesis by Th1 cells, natural killer cells and monocytes/macrophages. Several studies have suggested the potential application of IL-10 as an anti-inflammatory agent in the treatment of septic shock and as an immunosuppressive agent in certain T cell mediated autoimmune diseases.

    途径
    Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location, Cancer Immune Checkpoints
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