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HCV Core Protein Protein (AA 2-192) (beta-Gal)

HCV C 宿主: Hepatitis C Virus (HCV) Recombinant > 95 % pure as determined by 10 % PAGE (coomassie staining). WB, ELISA
产品编号 ABIN621534
发货至: 中国
  • 抗原 See all HCV Core Protein (HCV C) 蛋白
    HCV Core Protein (HCV C) (Hepatitis C Virus Core Protein (HCV C))
    蛋白类型
    Recombinant
    产品特性
    AA 2-192
    宿主
    Hepatitis C Virus (HCV)
    宿主
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    标记
    This HCV Core Protein protein is labelled with beta-Gal.
    应用范围
    Western Blotting (WB), ELISA
    序列
    mstnpkpqrk tkrntnrrpq dvkfpgvgqi vggvyllprr gprlgvratr ktsersqprg rrqpipkarr pegrtwaqpg ypwplygneg cgwagwllsp rgsrpswgpt dprrrsrnlg kvidtltcgf adlmgyiplv gaplggaara lahgvrvled gvnyatgnlp gcsfsiflla llscltvpa.
    特异性
    Immunoreactive with sera of HCV-infected individuals.
    产品特性
    Recombinant Hepatitis C Virus Nucleocapsid (core) 22 kDa
    纯化方法
    HCV-Core protein was purified by proprietary chromatographic technique.
    纯度
    > 95 % pure as determined by 10 % PAGE (coomassie staining).
    Top Product
    Discover our top product HCV C 蛋白
  • 应用备注
    HCV-Core Antigen is suitable for ELISA and Western blots, excellent antigen for detection of HCV with minimal specificity problems.
    限制
    仅限研究用
  • 缓冲液
    20mM Tris Hcl pH-8, 8M urea and 10mM beta-mercaptoethanol.
    储存条件
    -20 °C
  • 抗原
    HCV Core Protein (HCV C) (Hepatitis C Virus Core Protein (HCV C))
    Abstract
    HCV C 产品
    物质类
    Viral Protein
    背景
    The E. coli derived recombinant protein contains the HCV core nucleocapsid genotype 1b, immunodominant regions, AA 2-192, 22 kDa. The protein is fused with b-galactosidase (114 kDa) at N-terminus. Introduction: HCV is a small 50nm, enveloped, single-stranded, positive sense RNAvirus in the family Flaviviridae. HCV has a high rate of replication with approximately one trillion particles produced each day in an infected individual. Due to lack of proofreading by the HCV RNA polymerase, the HCV has an exceptionally high mutation rate, a factor that may help it elude the host's immune response. Hepatitis C virus is classified into six genotypes(1-6) with several subtypes within each genotype. The preponderance and distribution of HCV genotypes varies globally. Genotype is clinically important in determining potential response to interferon-based therapy and the required duration of such therapy. Genotypes 1 and 4 are less responsive to interferon-based treatment than are the other genotypes (2, 3, 5 and 6).
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