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OSCAR Protein (AA 19-282) (His tag)

OSCAR 宿主: 人 宿主: Baculovirus infected Insect Cells Recombinant > 90 % by SDS - PAGE SDS
产品编号 ABIN5855171
发货至: 中国
  • 抗原 See all OSCAR 蛋白
    OSCAR (Osteoclast Associated Receptor (OSCAR))
    蛋白类型
    Recombinant
    产品特性
    AA 19-282
    宿主
    • 6
    • 3
    资源
    • 3
    • 3
    • 2
    • 1
    Baculovirus infected Insect Cells
    标记
    This OSCAR protein is labelled with His tag.
    应用范围
    SDS-PAGE (SDS)
    序列
    DITPSVPPAS YHPKPWLGAQ PATVVTPGVN VTLRCRAPQP AWRFGLFKPG EIAPLLFRDV SSELAEFFLE EVTPAQGGSY RCCYRRPDWG PGVWSQPSDV LELLVTEELP RPSLVALPGP VVGPGANVSL RCAGRLRNMS FVLYREGVAA PLQYRHSAQP WADFTLLGAR APGTYSCYYH TPSAPYVLSQ RSEVLVISWE GEGPEARPAS SAPGMQAPGP PPSDPGAQAP SLSSFRPRGL VLQPLLPQTQ DSWDPAPPPS DPGVHHHHHH
    纯度
    > 90 % by SDS - PAGE
    内毒素水平
    < 1.0 EU per 1ug of protein (determined by LAL method)
    Top Product
    Discover our top product OSCAR 蛋白
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    缓冲液
    Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
  • 抗原
    OSCAR (Osteoclast Associated Receptor (OSCAR))
    别名
    OSCAR (OSCAR 产品)
    别名
    OSCAR Protein, mOSCAR-M3 Protein, mOSCAR Protein, mOSCAR-M1 Protein, mOSCAR-M2 Protein, PIGR3 Protein, PIgR-3 Protein, RGD1559897 Protein, osteoclast associated, immunoglobulin-like receptor Protein, osteoclast-associated immunoglobulin-like receptor Protein, osteoclast associated receptor Protein, OSCAR Protein, LOC748876 Protein, Oscar Protein
    背景
    OSCAR, also known as osteoclast-associated immunoglobulin-like receptor isoform 6, is an activating receptor expressed by human myeloid cells. It is a receptor for surfactant protein D that activates TNF-alpha release from human CCR2+ inflammatory monocytes. It is an FcRgamma-associated receptor that is expressed by myeloid cells and is involved in antigen presentation and activation of human dendritic cells. Its expression is detected specifically in preosteoclasts or mature osteoclasts. It is upregulated on monocytes from rheumatoid arthritis (RA) patients with active disease, and these monocytes show an increased proosteoclastogenic potential. Recombinant human OSCAR, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
    分子量
    29.2kDa (270aa) 40-57kDa (SDS-PAGE under reducing conditions)
    NCBI登录号
    NP_001269278
    UniProt
    Q8IYS5
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