1110007F23Rik Protein, Magp-36 Protein, zgc:77076 Protein, microfibril-associated glycoprotein 4 Protein, microfibrillar-associated protein 4 Protein, microfibril associated protein 4 S homeolog Protein, microfibril associated protein 4 Protein, CpipJ_CPIJ000434 Protein, CpipJ_CPIJ006120 Protein, CpipJ_CPIJ010089 Protein, CpipJ_CPIJ018551 Protein, CpipJ_CPIJ020296 Protein, mfap4 Protein, mfap4.S Protein, MFAP4 Protein, Mfap4 Protein
背景
MFAP4, also as known as microfibrillar-associated protein 4, belongs to Fibrinogen protein family and contains 1 fibrinogen C-terminal domain. This protein has similarity to a bovine microfibril-associated protein. The protein has binding specificities for both collagen and carbohydrate. It is thought to be an extracellular matrix protein which is involved in cell adhesion or intercellular interactions. Deletion of MFAP4 was found in 30 of 31 patients with Smith-Magenis syndrome (SMS), a clinically recognizable multiple congenital anomaly/mental retardation syndrome. Recombinant human MFAP4, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
分子量
27.5kDa (243aa) 28-40KDa (SDS-PAGE under reducing conditions.)