HRMT1L3 Protein, 2010005E20Rik Protein, 2410018A17Rik Protein, AL033309 Protein, Hrmt1l3 Protein, PRMT3 Protein, hrmt1l3 Protein, zgc:112498 Protein, ARABIDOPSIS THALIANA PROTEIN ARGININE METHYLTRANSFERASE 3 Protein, ATPRMT3 Protein, protein arginine methyltransferase 3 Protein, protein arginine methyltransferase 3 Protein, protein arginine N-methyltransferase 3 Protein, protein arginine methyltransferase 3 S homeolog Protein, PRMT3 Protein, Prmt3 Protein, prmt3 Protein, prmt3.S Protein
背景
PRMT3, as known as protein arginine N-methyltransferase 3, belongs to the protein arginine methyltransferase family. This enzyme catalyzes the methylation of guanidino nitrogens of arginyl residues of proteins. It acts on 40S ribosomal protein S2 (rpS2), which is its major in-vivo substrate, and is involved in the proper maturation of the 80S ribosome. Recombinant human PRMT3, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.