zgc:65973 Protein, rpa39 Protein, rpa40 Protein, rpa5 Protein, rpac1 Protein, POLR1C Protein, 40kDa Protein, AA409007 Protein, AA959927 Protein, AL024089 Protein, Polr1e Protein, RPA40 Protein, Rpo1-1 Protein, Ac2-127 Protein, RPA39 Protein, RPA5 Protein, RPAC1 Protein, TCS3 Protein, polymerase (RNA) I polypeptide C Protein, RNA polymerase I subunit C Protein, polymerase (RNA) I polypeptide C L homeolog Protein, polymerase (RNA) I polypeptide C, 30kDa Protein, polr1c Protein, POLR1C Protein, polr1c.L Protein, Polr1c Protein
背景
POLR1C is a subunit of both RNA polymerase I and RNA polymerase III complexes. The encoded protein is part of the Pol core element. Defects in this gene have been associated with Treacher Collins syndrome (TCS). Recombinant human POLR1C protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.