HCV 1b NS5B Protein (AA 2634-2752) (His tag)
HCV NS5b
宿主: Hepatitis C Virus (HCV)
宿主: 大肠杆菌（E. Coli）
Recombinant
> 90 % by SDS - PAGE
SDS
1 image
-
- 抗原 See all HCV 1b NS5B (HCV NS5b) products
- HCV 1b NS5B (HCV NS5b) (Hepatitis C Virus NS5b (HCV NS5b))
- 蛋白类型
- Recombinant
- 产品特性
- AA 2634-2752
- 宿主
- Hepatitis C Virus (HCV)
- 资源
- 大肠杆菌（E. Coli）
- 标记
- This HCV 1b NS5B protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSPMGF SYDTRCFDST VTESDIRTEE AIYQCCDLDP QARVAIKSLT ERLYVGGPLT NSRGENCGYR RCRASGVLTT SCGNTLTCYI KARAACRAAG LQDCTMLVCG DDLVVICESA GVQED
- 纯度
- > 90 % by SDS - PAGE
-
- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 0.25 mg/mL
- 缓冲液
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 0.15M NaCl, 10 % glycerol, 1 mM DTT
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
-
- 抗原
- HCV 1b NS5B (HCV NS5b) (Hepatitis C Virus NS5b (HCV NS5b))
- 别名
- HCV-NS5b (HCV NS5b 产品)
- 物质类
- Viral Protein
- 背景
- Hepatitis C virus genotype 1 is a core protein packages viral RNA to form a viral nucleocapsid, and promotes virion budding. It modulates viral translation initiation by interacting with HCV IRES and 40S ribosomal subunit and also regulates many host cellular functions such as signaling pathways and apoptosis. It prevents the establishment of cellular antiviral state by blocking the interferon-alpha/beta (IFN-alpha/beta) and IFN-gamma signaling pathways and by inducing human STAT1 degradation. NS5B is a RNA-dependent RNA polymerase that plays an essential role in the virus replication. Recombinant HCV(Hepatitis C Virus) NS5b protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- 分子量
- 17.0 kDa (155aa) confirmed by MALDI-TOF
- NCBI登录号
- NP_671491
-
You are here:
