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RAMP1 Protein (AA 27-117) (His tag)

RAMP1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 80 % by SDS - PAGE SDS
产品编号 ABIN5853491
发货至: 中国
  • 抗原 See all RAMP1 蛋白
    RAMP1 (Receptor (G Protein-Coupled) Activity Modifying Protein 1 (RAMP1))
    蛋白类型
    Recombinant
    产品特性
    AA 27-117
    宿主
    • 3
    • 1
    • 1
    • 1
    • 1
    资源
    • 3
    • 2
    • 2
    大肠杆菌(E. Coli)
    标记
    This RAMP1 protein is labelled with His tag.
    应用范围
    SDS-PAGE (SDS)
    序列
    MGSSHHHHHH SSGLVPRGSH MGSCQEANYG ALLRELCLTQ FQVDMEAVGE TLWCDWGRTI RSYRELADCT WHMAEKLGCF WPNAEVDRFF LAVHGRYFRS CPISGRAVRD PPGS
    纯度
    > 80 % by SDS - PAGE
    Top Product
    Discover our top product RAMP1 蛋白
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    说明

    Denatured

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    缓冲液
    Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 0.4M urea, 10 % glycerol
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
  • 抗原
    RAMP1 (Receptor (G Protein-Coupled) Activity Modifying Protein 1 (RAMP1))
    别名
    RAMP1 (RAMP1 产品)
    别名
    RAMP1 Protein, MGC147096 Protein, 9130218E19Rik Protein, receptor activity modifying protein 1 Protein, receptor (G protein-coupled) activity modifying protein 1 Protein, receptor (calcitonin) activity modifying protein 1 Protein, RAMP1 Protein, ramp1 Protein, Ramp1 Protein
    背景
    RAMP is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP1) protein, CRLR functions as a CGRP receptor. The RAMP1 protein is involved in the terminal glycosylation, maturation, and presentation of the CGRP receptor to the cell surface. Recombinant human RAMP1 protein, fused to His-tag at N-terminus, was expressed in E.coli.
    分子量
    12.9 kDa (114aa)
    NCBI登录号
    NP_005846
    UniProt
    O60894
    途径
    cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of Carbohydrate Metabolic Process
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