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RAPSN Protein (AA 1-412) (His tag)

RAPSN 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 85 % by SDS - PAGE SDS
产品编号 ABIN5853342
发货至: 中国
  • 抗原 See all RAPSN 蛋白
    RAPSN (Receptor-Associated Protein of The Synapse (RAPSN))
    蛋白类型
    Recombinant
    产品特性
    AA 1-412
    宿主
    • 4
    • 3
    • 1
    • 1
    资源
    • 2
    • 2
    • 2
    • 2
    • 1
    大肠杆菌(E. Coli)
    标记
    This RAPSN protein is labelled with His tag.
    应用范围
    SDS-PAGE (SDS)
    序列
    MGSSHHHHHH SSGLVPRGSH MGSMGQDQTK QQIEKGLQLY QSNQTEKALQ VWMKVLEKGS DLVGRFRVLG CLVTAHSEMG RYKEMLKFAV VQIDTARGLE DADFLLESYL NLARSNEKLC EFHKTISYCK TCLGLPGTRA GAQLGGQVSL SMGNAFLGLS LFQKALESFE KALRYAHNND DTMLECRVCC SLGSFYAQVK DYEKALFFPC KAAELVNDYG KGWSLKYRAM SQYHMAVAYR LLGHLGSAME CCEESMKIAL QHGDRPLQAL CLLCFADIHR SRGDLETAFP RYDSAMSIMT EIGNRLGQVH VLLGVAKCWM ARKVQDKALD AIEKAQDLAE EVGNKLSQLK LHCLSESIYR SKGLQRELRT HVVRFHECVE ETELYCGLCG ESIGERNSRL QALPCSHIFH LRCLQNNGTR SCPNCRRSSM KPGFV
    纯度
    > 85 % by SDS - PAGE
    Top Product
    Discover our top product RAPSN 蛋白
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    说明

    Denatured

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5 mg/mL
    缓冲液
    Liquid. 20  mM Tris-HCl buffer (  pH 8.0) containing 10 % glycerol 0.4M urea
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
  • 抗原
    RAPSN (Receptor-Associated Protein of The Synapse (RAPSN))
    别名
    RAPSN (RAPSN 产品)
    别名
    RAPSN Protein, RAPSYN Protein, RNF205 Protein, 43kDa Protein, Nraps Protein, Raps Protein, rapsyn Protein, receptor associated protein of the synapse Protein, receptor associated protein of the synapse S homeolog Protein, receptor-associated protein of the synapse Protein, receptor-associated protein of the synapse, 43kD Protein, RAPSN Protein, rapsn.S Protein, Rapsn Protein, rapsn Protein
    背景
    43 kDa receptor-associated protein of the synapse, also known as RAPSN, is expressed in the postsynaptic membrane of skeletal muscle. RAPSN is required for the clustering of nicotinic acetylcholine receptors (nAChR). It self-associates through at least two of its seven tetra-tricopeptide repeats (TPRs). RAPSN interacts with the large intracellular domain of the nAChR a subunit through the hydrophobic surface of the coiled-coil domain. This protein modifies trafficking of AChR within the cell. Overexpression inhibits agrin-induced AChR clustering pathway. Recombinant human RAPSN protein, fused to His-tag at N-terminus, was expressed in E.coli.
    分子量
    48.8 kDa (435aa)
    NCBI登录号
    NP_033049
    UniProt
    P12672
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