OBFC2A Protein (AA 1-204) (His tag)
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- 抗原 See all OBFC2A 蛋白
- OBFC2A (Oligonucleotide/oligosaccharide-Binding Fold Containing 2A (OBFC2A))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-204
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This OBFC2A protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- MGSSHHHHHH SSGLVPRGSH MGSMNRVNDP LIFIRDIKPG LKNLNVVFIV LEIGRVTKTK DGHEVRSCKV ADKTGSITIS VWDEIGGLIQ PGDIIRLTRG YASMWKGCLT LYTGRGGELQ KIGEFCMVYS EVPNFSEPNP DYRGQQNKGA QSEQKNNSMN SNMGTGTFGP VGNGVHTGPE SREHQFSHAG RSNGRGLINP QLQGTASNQT VMTTISNGRD PRRAFKR
- 纯度
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product OBFC2A 蛋白
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Oligonucleotide/oligosaccharide-Binding Fold Containing 2A (OBFC2A) (AA 1-204) protein (GST tag)
OBFC2A 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Oligonucleotide/oligosaccharide-Binding Fold Containing 2A (OBFC2A) (AA 1-204) protein (Strep Tag)Crystallography grade OBFC2A 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
Oligonucleotide/oligosaccharide-Binding Fold Containing 2A (OBFC2A) (AA 1-198) protein (Strep Tag)Crystallography grade OBFC2A 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
Oligonucleotide/oligosaccharide-Binding Fold Containing 2A (OBFC2A) (AA 1-204), (full length) protein (His-SUMO Tag)OBFC2A 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.5 mg/mL
- 缓冲液
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 0.2M NaCl, 50 % glycerol, 2 mM DTT
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- 抗原
- OBFC2A (Oligonucleotide/oligosaccharide-Binding Fold Containing 2A (OBFC2A))
- 别名
- NABP1 (OBFC2A 产品)
- 别名
- OBFC2A Protein, SOSS-B2 Protein, SSB2 Protein, 4930434H03Rik Protein, 4930442A21Rik Protein, 4930488J04Rik Protein, 4933440J18Rik Protein, 5830411E10Rik Protein, AI852561 Protein, Nbp1 Protein, Obfc2a Protein, Ssb2 Protein, RGD1306658 Protein, nucleic acid binding protein 1 Protein, NABP1 Protein, Nabp1 Protein
- 背景
- Nucleic acid binding protein 1, also known as NABP1, is component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. In the SOSS complex, the protein acts as a sensor of single-stranded DNA that binds to single-stranded DNA, in particular to polypyrimidines. The SOSS complex associates with DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. This protein is required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways. Recombinant human NABP1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- 分子量
- 24.8 kDa (227aa) confirmed by MALDI-TOF
- NCBI登录号
- NP_001026886
- UniProt
- Q96AH0
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