GZMK Protein (AA 27-264) (His tag)
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- 抗原 See all GZMK 蛋白
- GZMK (Granzyme K (Granzyme 3, Tryptase II) (GZMK))
- 蛋白类型
- Recombinant
- 产品特性
- AA 27-264
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 标记
- This GZMK protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- MGSSHHHHHH SSGLVPRGSH MGSIIGGKEV SPHSRPFMAS IQYGGHHVCG GVLIDPQWVL TAAHCQYRFT KGQSPTVVLG AHSLSKNEAS KQTLEIKKFI PFSRVTSDPQ SNDIMLVKLQ TAAKLNKHVK MLHIRSKTSL RSGTKCKVTG WGATDPDSLR PSDTLREVTV TVLSRKLCNS QSYYNGDPFI TKDMVCAGDA KGQKDSCKGD SGGPLICKGV FHAIVSGGHE CGVATKPGIY TLLTKKYQTW IKSNLVPPHT N
- 纯度
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product GZMK 蛋白
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 说明
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Denatured
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.5 mg/mL
- 缓冲液
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 0.4M urea, 10 % glycerol
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- 抗原
- GZMK (Granzyme K (Granzyme 3, Tryptase II) (GZMK))
- 别名
- GZMK (GZMK 产品)
- 别名
- TRYP2 Protein, granzyme K Protein, GZMK Protein, Gzmk Protein
- 背景
- GZMK is a member of a group of related serine proteases from the cytoplasmic granules of cytotoxic lymphocytes. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here lacks consensus sequences for N-glycosylation present in other granzymes. Recombinant human GZMK protein, fused to His-tag at N-terminus, was expressed in E.coli.
- 分子量
- 28.2 kDa (261aa)
- NCBI登录号
- NP_002095
- UniProt
- P49863
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