GREM2 Protein (AA 22-168) (His tag)
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- 抗原 See all GREM2 蛋白
- GREM2 (Gremlin 2 (GREM2))
- 蛋白类型
- Recombinant
- 产品特性
- AA 22-168
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 标记
- This GREM2 protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- MGSSHHHHHH SSGLVPRGSH MGSRKNRPAG AIPSPYKDGS SNNSERWQHQ IKEVLASSQE ALVVTERKYL KSDWCKTQPL RQTVSEEGCR SRTILNRFCY GQCNSFYIPR HVKKEEESFQ SCAFCKPQRV TSVLVELECP GLDPPFRLKK IQKVKQCRCM SVNLSDSDKQ
- 纯度
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product GREM2 蛋白
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 说明
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Denatured
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 0.4M urea, 10 % glycerol
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- 抗原
- GREM2 (Gremlin 2 (GREM2))
- 别名
- GREM2 (GREM2 产品)
- 别名
- prdc Protein, zgc:112207 Protein, RGD1560008 Protein, Gremlin2 Protein, Prdc Protein, CKTSF1B2 Protein, DAND3 Protein, PRDC Protein, gremlin 2, DAN family BMP antagonist Protein, gremlin 2, DAN family BMP antagonist b Protein, gremlin 2, cysteine knot superfamily Protein, GREM2 Protein, grem2b Protein, grem2 Protein, Grem2 Protein
- 背景
- GREM2 is a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this protein belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this protein may play a role in regulating organogenesis, body patterning, and tissue differentiation. Recombinant human GREM2 protein, fused to His-tag at N-terminus, was expressed in E.coli.
- 分子量
- 19 kDa (170aa)
- NCBI登录号
- NP_071914
- UniProt
- Q9H772
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