MECOM Protein (AA 1-169) (His tag)
-
- 抗原 See all MECOM 蛋白
- MECOM (MDS1 and EVI1 Complex Locus (MECOM))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-169
-
宿主
- 人
-
资源
- 大肠杆菌(E. Coli)
- 标记
- This MECOM protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- MGSSHHHHHH SSGLVPRGSH MGSMRSKGRA RKLATNNECV YGNYPEIPLE EMPDADGVAS TPSLNIQEPC SPATSSEAFT PKEGSPYKAP IYIPDDIPIP AEFELRESNM PGAGLGIWTK RKIEVGEKFG PYVGEQRSNL KDPSYGWEVH LPRSRRVSVH SWLYLGKRSS DVGIAFSQAD VYMPGLQCAF LS
- 纯度
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product MECOM 蛋白
-
-
- 应用备注
- Optimal working dilution should be determined by the investigator.
- 说明
-
Denatured
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 0.25 mg/mL
- 缓冲液
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing , 10 % glycerol, 0.4M urea
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
-
- 抗原
- MECOM (MDS1 and EVI1 Complex Locus (MECOM))
- 别名
- MDS1 (MECOM 产品)
- 别名
- AML1-EVI-1 Protein, EVI1 Protein, MDS1 Protein, MDS1-EVI1 Protein, PRDM3 Protein, D630039M04Rik Protein, Evi-1 Protein, Evi1 Protein, Jbo Protein, Mds Protein, Mds1 Protein, Mds1-Evi1 Protein, Prdm3 Protein, Znfpr1b1 Protein, evi1 Protein, im:7140716 Protein, prdm3 Protein, evi-1 Protein, mecom Protein, mecom-a Protein, mecom-b Protein, xEvi-1 Protein, evi1-B Protein, MDS1 and EVI1 complex locus Protein, MDS1 and EVI1 complex locus L homeolog Protein, MDS1 and EVI1 complex locus S homeolog Protein, MECOM Protein, Mecom Protein, mecom Protein, mecom.L Protein, mecom.S Protein
- 背景
- MDS1 is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene. Recombinant human MDS1 protein, fused to His-tag at N-terminus, was expressed in E.coli
- 分子量
- 21.1kDa (192aa)
- NCBI登录号
- NP_004982
-