Optimal working dilution should be determined by the investigator.
限制
仅限研究用
状态
Liquid
浓度
0.1-2 mg/mL
缓冲液
20 mM Tris-HCl based buffer, pH 8.0
储存条件
-80 °C,4 °C,-20 °C
储存方法
Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
FLI Protein, FLIL Protein, Fli1 Protein, 3632430F08Rik Protein, Fliih Protein, im:7141769 Protein, DKFZp459O043 Protein, flightless Protein, FLII, actin remodeling protein Protein, flightless I actin binding protein Protein, protein flightless-1 homolog Protein, FLII, actin remodeling protein S homeolog Protein, Protein flightless-1 homolog Protein, FLII Protein, Flii Protein, flii Protein, LOC585336 Protein, LOC100640615 Protein, flii.S Protein, fli-1 Protein
背景
May play a role as coactivator in transcriptional activation by hormone-activated nuclear receptors (NR) and acts in cooperation with NCOA2 and CARM1. Involved in estrogen hormone signaling . Essential for early bryonic development. May play a role in regulation of cytoskeletal rearrangents involved in cytokinesis and cell migration, by inhibiting Rac1-dependent paxillin phosphorylation.