TEAD1 Protein (AA 1-426, full length) (His tag)
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- 抗原 See all TEAD1 蛋白
- TEAD1 (TEA Domain Family Member 1 (SV40 Transcriptional Enhancer Factor) (TEAD1))
- 蛋白类型
- Recombinant
- 产品特性
- full length, AA 1-426
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宿主
- 人
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资源
- 酵母菌
- 标记
- This TEAD1 protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- MEPSSWSGSE SPAENMERMS DSADKPIDND AEGVWSPDIE QSFQEALAIY PPCGRRKIIL SDEGKMYGRN ELIARYIKLR TGKTRTRKQV SSHIQVLARR KSRDFHSKLK DQTAKDKALQ HMAAMSSAQI VSATAIHNKL GLPGIPRPTF PGAPGFWPGM IQTGQPGSSQ DVKPFVQQAY PIQPAVTAPI PGFEPASAPA PSVPAWQGRS IGTTKLRLVE FSAFLEQQRD PDSYNKHLFV HIGHANHSYS DPLLESVDIR QIYDKFPEKK GGLKELFGKG PQNAFFLVKF WADLNCNIQD DAGAFYGVTS QYESSENMTV TCSTKVCSFG KQVVEKVETE YARFENGRFV YRINRSPMCE YMINFIHKLK HLPEKYMMNS VLENFTILLV VTNRDTQETL LCMACVFEVS NSEHGAQHHI YRLVKD
- 纯化方法
- SDS-PAGE
- 纯度
- > 90 %
- Top Product
- Discover our top product TEAD1 蛋白
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TEA Domain Family Member 1 (SV40 Transcriptional Enhancer Factor) (TEAD1) (AA 1-60) protein (GST tag)
TEAD1 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
TEA Domain Family Member 1 (SV40 Transcriptional Enhancer Factor) (TEAD1) (AA 1-426) protein (Strep Tag)Crystallography grade TEAD1 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
TEA Domain Family Member 1 (SV40 Transcriptional Enhancer Factor) (TEAD1) (AA 1-426) protein (Strep Tag)Crystallography grade TEAD1 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.1-2 mg/mL
- 缓冲液
- 20 mM Tris-HCl based buffer, pH 8.0
- 储存条件
- -80 °C,4 °C,-20 °C
- 储存方法
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- 抗原
- TEAD1 (TEA Domain Family Member 1 (SV40 Transcriptional Enhancer Factor) (TEAD1))
- 别名
- TEAD1 (TEAD1 产品)
- 别名
- tead1 Protein, zgc:63696 Protein, TEAD1 Protein, xtead1 Protein, 2610024B07Rik Protein, B230114H05Rik Protein, Gtrgeo5 Protein, TEAD-1 Protein, TEF-1 Protein, Tcf13 Protein, mTEF-1 Protein, AA Protein, NTEF-1 Protein, REF1 Protein, TCF-13 Protein, TCF13 Protein, XNTEF-1 Protein, xlNTEF-1 Protein, TEA domain family member 1a Protein, TEA domain transcription factor 1 Protein, TEA domain family member 1 (SV40 transcriptional enhancer factor) Protein, TEA domain family member 1 Protein, TEA domain family member 1 (SV40 transcriptional enhancer factor) S homeolog Protein, TEA domain family member 1b Protein, tead1a Protein, TEAD1 Protein, tead1 Protein, Tead1 Protein, tead1.S Protein, tead1b Protein
- 背景
- Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (T) induction. Binds specifically and cooperatively to the SPH and GT-IIC 'enhansons' (5'-GTGGAATGT-3') and activates transcription in vivo in a cell-specific manner. The activation function appears to be mediated by a limiting cell-specific transcriptional intermediary factor (TIF). Involved in cardiac development. Binds to the M-CAT motif.
- 分子量
- 49.95 kDa
- UniProt
- P28347
- 途径
- Regulation of Lipid Metabolism by PPARalpha
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